介入封堵房间隔术对患者心率的影响  

Influence of interventional closure on heart rate in patients with atrial septal defect

作　　者：段宇辰 薛凤华[1] 洪名扬 李元十[1] 高倩萍[1] 富路[1] DUAN Yu-chen;XUE Feng-hua;HONG Ming-yang;LI Yuan-shi;GAO Qian-ping;FU Lu(Department of Cardiology,First Affiliated Hospital of Harbin Medical University,Harbin,Heilongjiang,150001,China)

机构地区：[1]哈尔滨医科大学附属第一医院心内科

出　　处：《心血管康复医学杂志》2019年第6期776-779,共4页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：目的:探讨介入封堵房间隔缺损术对患者心率的影响。方法:选择我院经皮介入封堵房间隔缺损的63例患者,比较手术前后心率的变化,并分析心率与年龄、封堵伞大小以及术前肺动脉压力的相关性。结果:经皮介入封堵房间隔缺损术后心率较术前显著降低[(64.87±10.65)次/min比(75.22±8.23)次/min,P=0.001];Pearson相关分析显示,术后心率变化与年龄、应用封堵伞大小、肺动脉收缩压无关(r=0.017~0.182,P均>0.05)。但术前出现肺动脉收缩压升高(≥25mmHg)的患者术后心率下降幅度显著大于术前未出现肺动脉高压患者[(11.35±10.73)次/min比(2.28±9.81)次/min,P=0.038]。结论:经皮介入封堵房间隔缺损术后患者心率会出现下降,术前出现肺动脉高压可作为术后心率下降的风险预测指标。Objective:To explore influence of interventional closure on heart rate in patients with atrial septal defect.Methods:A total of 63 patients with atrial septal defect undergoing percutaneous interventional closure in our hospital were selected.Heart rate was compared before and after surgery,and correlation among heart rate,age,occlude size and preoperative pulmonary artery pressure was analyzed.Results:Compared with before surgery,there was significant reduction in heart rate[(75.22±8.23)beats/min vs.(64.87±10.65)beats/min]after percutaneous interventional closure of atrial septal defect,P=0.001;Pearson correlation analysis indicated that postoperative heart rate change was not correlated with age,occluder size and pulmonary artery systolic pressure(PASP)(r=0.017-0.182,P>0.05 all).Compared with patients without preoperative pulmonary artery hypertension,there was significant rise in postoperative reduction amplitude of heart rate[(2.28±9.81)beats/min vs.(11.35±10.73)beats/min]in those with preoperative elevated pulmonary systolic pressure(≥25mmHg),P=0.038.Conclusion:After percutaneous interventional closure,heart rate significantly decreases in patients with atrial septal defect.Presence of preoperative pulmonary artery hypertension can be regarded as a risk predictor for postoperative heart rate reduction.

关 键 词：房间隔缺损 心率 心间隔封堵装置 

分 类 号：R541.1[医药卫生—心血管疾病]