Ⅱ-Ⅲ度羊水污染孕妇行剖宫产分娩对新生儿缺氧缺血性脑病发生率的影响  

Effect of cesarean delivery in pregnant women with Ⅱ and Ⅲ degree amniotic fluid on the incidence of hypoxic-ischemic encephalopathy in newborns

作　　者：赵新敏[1] ZHAO Xinmin(The First Affiliated Hospital of Nanyang Medical College,Nanyang 473058,China)

机构地区：[1]南阳医学高等专科学校第一附属医院

出　　处：《中国实用神经疾病杂志》2019年第22期2504-2509,共6页Chinese Journal of Practical Nervous Diseases

摘　　要：目的探讨Ⅱ、Ⅲ度羊水污染孕妇行剖宫产分娩对新生儿缺氧缺血性脑病(HIE)发生率的影响。方法选取2015-10-2018-10南阳医学高等专科学校第一附属医院收治的114例羊水污染新生儿,根据羊水污染程度分为A组和B组各57例。A组羊水污染程度为Ⅱ度,B组羊水污染程度为Ⅲ度。选择同期50例羊水污染程度为Ⅰ度新生儿作为对照组。统计3组新生儿评分(Apgar),并对比不良妊娠结局(HIE、肺炎、窒息)。结果 A组Apgar评分4~6分占比高于对照组,7~10分占比低于对照组,差异均有统计学意义(P<0.05);B组1~3分、4~6分所占比例均高于对照组,差异有统计学意义(P<0.05);A组Apgar评分各分值所占比例与B组相比,差异无统计学意义(P>0.05);A组HIE、窒息、肺炎发生率(1.75%、8.77%、5.26%)低于B组(15.78%、22.80%、19.29%),差异有统计学意义(P<0.05);B组HIE、窒息、肺炎发生率(15.78%、22.80%、19.29%)高于对照组(2.00%、8.00%、4.00%),差异有统计学意义(P<0.05)。结论Ⅱ、Ⅲ度羊水污染孕妇行剖宫产分娩均可提高HIE发生率,故早期予以预防性治疗,对降低新生儿发病率及致残率具有临床指导意义。Objective To investigate the effect of cesarean section delivery in pregnant women with Ⅱ and Ⅲ degree amniotic fluid on the incidence of neonatal hypoxic-ischemic encephalopathy(HIE).Methods From October 2015 to October 2018,114 cases of amniotic fluid-contaminated newborns admitted to the First Affiliated Hospital of Nanyang Medical College were selected and divided into group A and group B 57 cases according to the degree of amniotic fluid pollution.The degree of amniotic fluid pollution in group A was Ⅱ degree,and the degree of amniotic fluid pollution in group B was Ⅲ degree.Fifty neonates with a degree of amniotic fluid pollution of Ⅰ degree during the same period were selected as the control group.The neonatal scores(Apgar) of the three groups were counted,and adverse pregnancy outcomes(HIE,pneumonia,and asphyxia) were compared.Results The percentage of Apgar scores in group A was 4-6,which was higher than that in the control group,and the proportion of 7-10 points was lower than that in the control group,and the differences were statistically significant(P<0.05).Group B was 1 to 3 points and 6 to 4 points.The proportions were higher than those in the control group,and the differences were statistically significant(P<0.05).The proportions of Apgar scores in group A were not significantly different from those in group B(P>0.05).Suffocation,pneumonia(1.75%,8.77%,5.26%) were lower than those in group B(15.78%,22.80%,19.29%),and the difference was statistically significant(P<0.05);HIE,asphyxia,and pneumonia occurred in group B The rates(15.78%,22.80%,19.29%) were higher than those in the control group(2.00%,8.00%,4.00%),and the differences were statistically significant(P<0.05).Conclusion Cesarean section delivery in pregnant women with Ⅱ and Ⅲ degree amniotic fluid can increase the incidence of HIE,so early preventive treatment is of clinical significance to reduce the incidence and disability of newborns.

关 键 词：Ⅲ度羊水污染 Ⅱ度羊水污染 剖宫产 新生儿缺氧缺血性脑病 

分 类 号：R722.1[医药卫生—儿科]