视黄醇结合蛋白4早期评估冠状动脉粥样硬化的研究进展  

Research progress in retinol binding protein 4 for indicating coronary atherosclerotic heart disease in the early stage

作　　者：王潇[1] 潘一龙[1] 付茜 王琳琳 李晓东[1] WANG Xiao;PAN Yi-long;FU Xi;WANG Lin-lin;LIXiao-dong(Department of First Cardiovascular Medicine,Shengjing Hospital of China Medical University,Shenyang 110004,China)

机构地区：[1]中国医科大学附属盛京医院第一心血管内科

出　　处：《实用药物与临床》2019年第12期1328-1332,共5页Practical Pharmacy and Clinical Remedies

基　　金：“十二五”国家科技支撑计划(2014BAL11B04)

摘　　要：视黄醇结合蛋白4(Retinol binding protein,RBP4)是一种脂肪组织来源的蛋白质,具有重要的生理功能。近年研究发现,RBP4在冠心病的发生发展过程中起着至关重要的作用。RBP4可能早期提示冠状动脉粥样硬化的发生,并为冠状动脉的早期病变发出危险信号。本文就RBP4对于早期提示冠心病的近年研究成果进行综述。Retinol binding protein(RBP4)is a kind of fat tissue-derived protein,which can play an important physiological function.In recent years,a number of studies have found that RBP4 plays a crucial role in the occurrence and development of coronary heart disease.RBP4 may become an early indicator of coronary atherosclerotic heart disease and send out a dangerous signal for early coronary artery lesions.This article reviews the recent research results on RBP4 in the early stage of coronary heart disease.

关 键 词：视黄醇结合蛋白4 冠心病 冠状动脉粥样硬化 早期 

分 类 号：R54[医药卫生—心血管疾病]