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作 者:潘明明 陈枉枉 王艳[1] 王婧[1] 周正宇[1] PAN Ming-ming;CHEN Wang-wang;WANG Yan;WANG Jing;ZHOU Zheng-yu(Laboratory Animal Center,Soochow University,Suzhou 215123,China)
机构地区:[1]苏州大学实验动物中心
出 处:《实验动物与比较医学》2019年第6期489-495,共7页Laboratory Animal and Comparative Medicine
摘 要:控制实验动物屏障设施病原微生物不仅关乎实验动物质量和实验结果的可信度,更关系到人员健康和环境安全。在实验动物屏障设施的运行过程中,人员和物品的进出等可能带入病原微生物,因此屏障设施的日常卫生消毒至关重要。本文选取实验动物屏障设施中常用的6种消毒剂,对其性质、作用机理、毒性、职业健康安全和应用效果等方面进行综述,为实验动物屏障设施选取合理有效的消毒剂提供参考。Control of pathogenic micro-organisms in laboratory animal barrier facilities is not only related to the quality of laboratory animals, the credibility of experimental results, but also the health of personnel and the safety of the environment. However, during the daily operation of laboratory animal barrier facilities, pathogenic micro-organisms may be introduced via the entry and exit of personnel and articles, etc, so daily sanitation and disinfection of the barrier environment is very important. In this paper, 6 kinds of commonly used disinfectants for laboratory animal barrier facilities were selected, and their properties, mechanism of action, toxicity, occupational health and safety, effects and other parameters were summarized, so as to provide reference for selecting reasonable and effective disinfectants for laboratory animal barrier facilities.
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