正交实验优选痛风巴布膏剂的提取工艺  

Rthogonal design is preferred for extraction process of Gout babu paste

作　　者：谢鑫 侯晓杰 李玮 李慧 庹林波 杨肖衣 张建锋 XIE Xin;HOU Xiaojie;LI Wei;Li Hui;TUO Linbo;YANG Xiaoyi;ZHANG Jianfeng(Qingzhen Hospital of Traditional Chinese Medicine,Qing zhen 551400,China;School of Pharmacy,Guizhou University of Chinese Medicine,Guiyang 550025,China;Sinopharm Group Tongjitang(Guizhou)Pharmaceutical Co.,Ltd.Guiyang 550009,China)

机构地区：[1]贵州省清镇市中医医院,贵州清镇551400 [2]贵州中医药大学药学院,贵州贵阳550025 [3]国药集团同济堂(贵州)制药有限公司,贵州贵阳550009

出　　处：《中国民族民间医药》2019年第23期38-40,52,共4页Chinese Journal of Ethnomedicine and Ethnopharmacy

基　　金：贵州省中医药管理局中医药、民族医药科学技术研究课题:QZYY-2018-092;贵州省国内一流建设学科项目编号:(中药学)(GNYL[2017]008号);黔高教发[2017]158号-02-04号

摘　　要：目的:优选痛风巴布膏剂的最佳提取工艺。方法:以复方中马钱子碱含量和出膏率为考察指标,采用正交实验优选最佳提取工艺。结果:最佳提取工艺为提取2次,每次加水量为10倍,每次提取时间为0.5h。结论:正交实验优选的痛风巴布膏剂的提取工艺稳定、可行。Objective Optimize the best extraction process of gout Babu paste.Methods The optimum extraction technology was optimized by orthogonal experiment based on the content of brucine and the ratio of extract from brucellia chinensis Results The best extraction process is 2 extraction times,each time the water is added 10 times,each extraction time is 0.5 h.Conclusion The extraction technology of gout Babu paste optimized by orthogonal experiment is stable and feasible.

关 键 词：痛风巴布膏剂 正交实验 提取工艺 马钱子碱 

分 类 号：R284.2[医药卫生—中药学]