含二茂铁基偶氮苯水杨醛席夫碱的合成与表征  

Synthesis and Characterization of Azobenzene Salicylaldehyde Schiff Base Containing Ferrocene

作　　者：肖文杰 万屏南[1] 刘文琴[1] 崔汉峰[1] 苏婷婷 林艳[1] XIAO Wen-jie;WAN Pingnan;LIU Wen-qin;CUI Han-feng;SU Ting-ting;LIN Yan(School of Pharmacy,Jiangxi University of Traditional Chinese Medicine,Nanchang 330004,China)

机构地区：[1]江西中医药大学药学院

出　　处：《化学试剂》2019年第12期1317-1321,共5页Chemical Reagents

基　　金：国家自然科学基金资助项目(81560625);江西省教育厅科技项目(160829);江西省卫生厅中医药科技项目(2016B017);江西中医药大学研究生创新项目(JZYC18S05)

摘　　要：二茂铁席夫碱是一类重要的二茂铁衍生物,具有新颖的结构和特殊的性能,将二茂铁单元与具有分子开关性能的偶氮苯水杨醛有效对接,构建具有光控分子开关性能的简单模型。以碘代二茂铁为起始原料,经亲核取代、肼解反应得到氨基二茂铁,随后与具有不同取代基的偶氮苯水杨醛进行缩合反应,设计合成了5种结构新颖的含二茂铁结构单元的偶氮苯水杨醛席夫碱。目标产物的结构经1HNMR、13CNMR、红外光谱和元素分析进行确征。合成方法具有操作简单、反应条件不苛刻、后处理简单等优点。Ferrocene Schiff bases are important ferrocene derivatives with novel structures and special properties.A simple model was constructed with photocontrolled molecular switches that was effectively docked with azobenzyl salicylaldehyde and ferrocene unit.A series of novel azobenzene salicylaldehyde Schiff base containing ferrocene were designed and synthesized from condensation reaction with azobenzyl salicylaldehyde and aminoferrocene which obtained from nucleophilic substitution and hydrazine hydrolysis reaction using ferrocene iodide as a starting material.The structure of target products was confirmed by 1HNMR,13CNMR,infrared spectrum and elemental analysis.The synthetic method has the advantages of simple operation,less stringent reaction conditions and simple post-treatment.

关 键 词：二茂铁 偶氮苯 水杨醛 席夫碱 合成 

分 类 号：O625.64[理学—有机化学]