非新生儿破伤风诊疗规范  

Specifications for diagnosis and treatment of non-neonatal tetanus

作　　者：王传林[1] 刘斯[2] 陈庆军[3] 邵祝军[4] 吴纪峰[5] 范昭[6] 王培戈[7] 朱政纲[8] 兰频 李建国[10] 郑以山[11] 何武兵[12] 徐哲 唐卫东 逄金满[15] 班志红 杨树青 丁文涛[18] 郑希福 张齐龙[20] Wang Chuanlin;Liu Si;Chen Qingjun;Shao Zhujun;Wu Jifeng;Fan Zhao;Wang Peige;Zhu Zhenggang;Lan Pin;Li Jianguo;Zheng Yishan;He Wubing;Xu Zhe;Tang Weidong;Pang Jinman;Ban Zhihong;Yang Shuqing;Ding Wentao;Zheng Xifu;Zhang Qilong(Emergency Department/Trauma Center,Peking University People's Hospital,Beijing 100044.China;Department of Emergency,Peking University First Hospital,Beijing 100034,China;Emergency Department,Beijing Hepingli Hospital,Beijing 100013,China;National Institute for Communicable Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206、China;Surgical Department,Shijiazhuang Fifth Hospital,Shijiazhuang 050021,China;Emergency Department,Peking University Shenzhen Hospital,Shenzhen 518036,China;Emergency Department,The Affiliate Hospital of Qingdao Universityt Qingdao 266003,China;Wuhan Center for Disease Control and Prevention,Wuhan 430015,China;Department of Emergency,Lishui Hospital,Zhejiang University School of Medicine,Lishui 323000,China;Emergency Department,Hebe general hospital,Shijiazhuang 050051,China;Department of Critical Care Medicine,The Second Hospital of Nanjing,Nanjing 210003 China;Provincial clinical medical college,Fujian medical university,Fuzhou 350001,China;The centre of infectious diseases,the Fifth medical centre,PLA general hospital,Beijing100039,China;Suzhou Road Hospital,Xinjiang Autonomous Region People's Hospital,Department of Orthopedics,Urumqi 830000.China;Thyroid and breast surgery,The third hospital of Jinan,Jinan 250132,China;Emergency Department,Guangxi International Zhuang Medicine Hospital,Nanning 530200,China;Emergency Department,Chongqing Emergency Medical Center/Central Hospital of Chongqing University,Chongqing 400014,China;Department of General Surgery,Tianjin First Central Hospital,Tianjin 300192,China;Department of Orthopedic Surgery,First Affiliated Hospital,Dalian Medical University,Dalian 116011,China;Department of Emergency and Critical Care Medicine,The Jiangxi chest hospital,Nanchang 330006,China)

机构地区：[1]北京大学人民医院急诊科创伤救治中心,北京100044 [2]北京大学第一医院急诊科,100034 [3]北京市和平里医院急诊科,100013 [4]中国疾病预防控制中心传染病预防控制所,北京102206 [5]石家庄市第五医院外科,050021 [6]北京大学深圳医院急诊科,深圳518036 [7]青岛大学附属医院急诊科,266003 [8]武汉市疾病预防控制中心狂犬病门诊,430015 [9]浙江大学丽水医院急诊科,323000 [10]河北省人民医院急诊科,石家庄050051 [11]南京市第二医院重症医学科,210003 [12]心福建医科大学省立临床医学院,福州350001 [13]解放军总医院第五医学中心感染性疾病诊疗与研究中心二科,北京100039 [14]新疆自治区人民医院苏州路院区骨科,乌鲁木齐830000 [15]济南市第三人民医院两腺外科,250132 [16]广西国际壮医医院急诊科,南宁530200 [17]重庆市急救医疗中心重庆大学附属中心医院急诊部,400014 [18]天津市第一中心医院普通外科,300192 [19]大连医科大学附属第一医院骨科,116011 [20]江西省胸科医院急诊危重症医学科,南昌330006

出　　处：《中华预防医学杂志》2019年第12期1206-1211,共6页Chinese Journal of Preventive Medicine

摘　　要：破伤风分为新生儿破伤风和非新生儿破伤风。我国已于2012年消除了新生儿破伤风,但非新生儿破伤风仍是一个严重的公共卫生问题。非新生儿破伤风重症患者在无医疗干预的情况下,病死率接近100%.即使经过积极的综合治疗,全球范围病死率仍为30%~50%,是一种极为严重的潜在致命性疾病。为规范我国非新生儿破伤风诊疗行为,提高医疗质量,保障医疗安全,特制定本规范。本规范包括了非新生儿破伤风的病原学、流行病学、发病机制、临床表现及实验室检查、诊断、鉴别诊断、分级、治疗等方面内容。Tetanus consists of neonatal tetanus and non-neonatal tetanus.Although neonatal tetanus in China has been eliminated since 2012,non-neonatal tetanus remains a serious public health problem.Non-neonatal tetanus is a potential fatal disease,and the mortality rate of severe cases is almost 100%in the absence of medical intervention.Even with vigorous treatment,the mortality rate is still 30~50% globally.In order to standardize the diagnosis and treatment of non-neonatal tetanus in China,this specification is hereby formulated.This standard includes etiology,epidemiology,pathogenesis,clinical manifestations,laboratory tests,diagnosis,differential diagnosis,classification,grading and treatment of non-neonatal tetanus.

关 键 词：破伤风 规范 非新生儿 诊断 治疗 

分 类 号：R47[医药卫生—护理学]