红细胞分布宽度和血清C-反应蛋白与白蛋白比值对急性胰腺炎预后的预测价值探讨  

Significance of red blood cell distribution width and C-reactive protein/albumin levels in predicting prognosis of acute pancreatitis

作　　者：笪伟[1] DA Wei(The First Hospital of Anhui Medical University,Hefei 230022,China)

机构地区：[1]安徽医科大学第一附属医院急诊科,合肥230022

出　　处：《肝胆外科杂志》2019年第5期365-367,共3页Journal of Hepatobiliary Surgery

摘　　要：目的探讨红细胞分布宽度(red cell distribution width,RDW)和血清C-反应蛋白与白蛋白(CPR/albumin)的比值对急性胰腺炎(acute pancreatitis,AP)预后的预测价值.方法选取2017年1月—2018年12月安徽医科大学第一附属医院急诊科及急诊重症医学科收治的急性胰腺炎患者132例,根据急性生理与慢性健康评分Ⅱ(acute physiologic assessment and chronic health evaluation,APACHE-Ⅱ)评分分为轻症胰腺炎(mild acute pancreatitis,MAP)102例,重症胰腺炎(severe acute pancreatitis,SAP)30例.比较2组RDW和CPR/albumin的比值、住院天数和在重症医学科(intensive care unit,ICU)的天数、并发症.结果RDW在两组比较中无统计学意义(P=0.193),血清C-反应蛋白与白蛋白比值重症组明显高于轻症组(P<0.001).重症组也有更长的住院天数,包括普通病房和ICU(P=0.001,P=0.047).结论RDW不是急性胰腺炎预后预测的特异性指标,而血清C-反应蛋白与白蛋白比值却是一个急性胰腺炎预后预测的容易得到、可靠的指标.Objective The aim of this study was to determine the relationship between the red cell distribution width(RDW)value and the C-reactive protein(CRP)albumin ratio in patients with AP.Methods From January 2017 to December 2018 t a total of 132 patients with acute pancreatitis were selected from departments of emergency 、 intensive medicine in the first Affiliated Hospital of Anhui Medical University,AP cases were enrolled and divided into 2 groups according to the acute physiologic assessment and chronic health evaluation(APACHE-Ⅱ)criteria as moderate(102 cases)or severe pancreatitis(30 cases).The RDW and CRP/albumin values,length of hospitalization and stay in the intensive care unit(ICU),and the complications experienced were compared between these 2 groups.Results There was no statistically significant difference in the RDW value between the groups(P=0.193).The CRP/albumin values were significantly higher in the severe pancreatitis group compared with the moderate group(P<0.001).The severe AP group also had a longer period of hospital care,both overall and in the ICU(P=0.001,P=0.047).Conclusion RDW was not a specific marker for predicting prognosis in AP,but the CRP/albumin ratio is an easy-to-apply and reliable marker.

关 键 词：急性胰腺炎 C-反应蛋白/白蛋白 红细胞分布宽度 预后 

分 类 号：R658[医药卫生—外科学]