甘草提取工艺研究  

Research on extraction technology of glycyrrhizic acid from Radix Glycyrrhizae

作　　者：李越峰[1,2] 辛二旦 司昕蕾 边甜甜 曹瑞[1,2] 刘岩峥 LI Yuefeng;XIN Erdan;SI Xinlei;BIAN Tiantian;CAO Rui;LIU Yanzheng(University of Traditional Chinese Medicine of GanSu,Lanzhou Gansu 730000,China;key laboratory of standard and quality of Chinese medicine research of Gansu Lanzhou 730000,China;Gansu Provincial Cancer Hospital,Lanzhou Gansu 730050,China)

机构地区：[1]甘肃中医药大学,甘肃兰州730000 [2]甘肃省中药质量与标准研究重点实验室,甘肃兰州730000 [3]甘肃省肿瘤医院,甘肃兰州730050

出　　处：《中兽医医药杂志》2019年第6期44-47,共4页Journal of Traditional Chinese Veterinary Medicine

基　　金：重点研发计划-社会发展类(1204FKCA140);国家自然科学基金资助项目(81460611);国家教育部科学技术研究重点基金资助项目(212186);甘肃省自然科学基金资助项目(2010:1010RJZA212;2014:145 RJZA076);甘肃省财政厅高校基本科研业务费专项基金资金项目(2013-2);兰州市科技局项目(2014-1-188);甘肃省中医药管理局科研课题(GZK-2015-57)

摘　　要：目的:考察甘草的提取方法,优选甘草中甘草酸的最佳提取工艺。方法:以甘草酸的含量为指标,对不同提取方法进行筛选;以提取溶剂、浓度和提取时间为考察因素,采用正交试验L9(3^4)优选甘草酸的最佳提取工艺。结果:最佳提取方法为超声提取法;最佳提取工艺为50%乙醇超声30 min。结论:超声提取甘草酸含量高,且该工艺简便可行,易于实现工业化提取。Objective:To research the extraction method and select optimum extraction process of glycyrrhizic acid from Radix Glycyrrhizae.Method:The content of glycyrrhizic acid was used as the index to screen the different extraction methods.The optimum extraction process of glycyrrhizic acid was optimized by orthogonal test L9(3^4)with extraction solvent,concentration and extraction time as factors.The best extraction method was ultrasonic extraction.The optimal extraction process was 50%ethanol ultrasound for 30 min.Ultrasonic extraction of glycyrrhizic acid content was high,and the process was simple and feasible,easy to achieve industrial extraction.

关 键 词：甘草 甘草酸 正交试验 提取工艺 

分 类 号：S853.72[农业科学—临床兽医学]