脑室腹腔分流术后体温变化趋势与颅内感染的关系研究  

Relation between trend of temperature changes and intracranial infection after ventriculoperitoneal shunt

作　　者：张欢 何骁征[1] 叶衍娟[1] 张世忠[1] Zhang Huan;He Xiaozheng;Ye Yanjuan;Zhang Shizhong(National Key Clinical Specialty,Engineering Technology Research Center of Ministry of Education,Guangdong Institute of Neurosurgery,Guangdong Key Laboratory of Brain Function Repair and Regeneration,Department of Neurosurgery,Zhujiang Hospital of Southern Medical University,Guangzhou 510282,China)

机构地区：[1]国家临床重点专科,教育部工程技术研究中心,广东省脑功能修复与再生重点实验室,南方医科大学珠江医院神经外科,广州510282

出　　处：《中华神经医学杂志》2019年第12期1236-1240,共5页Chinese Journal of Neuromedicine

基　　金：广东省医学科学技术研究基金(A2015360)。

摘　　要：目的观察脑室腹腔分流术后患者体温的变化趋势,探讨其与术后颅内感染的关系。方法选择南方医科大学珠江医院神经外科自2015年1月至2018年12月行脑室腹腔分流术的272例患者,根据患者术后是否发生颅内感染分为感染组与未感染组。再根据术后出现颅内感染的时间将感染患者分为早期感染组和延迟感染组。比较各组患者术后当天及术后第1、3、5、7天的体温及发热情况。结果272例患者中发生颅内感染25例(9.19%)(早期感染21例,延迟感染4例),未感染247例(90.81%)。与未感染组比较,感染组患者术后第3、5、7天发热率较高,体温较高,差异均有统计学意义(P<0.05)。早期感染组与延迟感染组患者术后当天及术后第1、3、5、7天发热率及体温差异均无统计学意义(P>0.05)。结论脑室腹腔分流术后患者发热率较高,体温下降较快,自第3天起仍有发热则可能为术后颅内感染,应提早考虑抗感染治疗。Objective To observe the trend of temperature changes after ventriculoperitoneal shunt and its relation with postoperative infection.Methods A retrospective cohort study was conducted on 272 patients underwent ventriculoperitoneal shunt in our hospital from January 2015 to December 2018.Patients were divided into infected group and non-infected group according to whether intracranial infection occurred after surgery.According to the occurring time of postoperative intracranial infection,patients were divided into early infection group and delayed infection group.Temperature levels of all patients were monitored on the surgery day,and on the first,3rd,5th and 7th d of surgery,and the temperature changes and fever rate of the two groups were compared.Results Among 272 patients,intracranial infection occurred in 25(9.19%),including 21 with early infection and 4 with delayed infection,and un-infection in 247(90.81%).As compared with those in the non-infected group,the fever rate and body temperature of the infected group were significantly higher on the 3rd,5th and 7th d after surgery(P<0.05).There was no significant difference in fever rate and body temperature changes between the early infection group and the delayed infection group on the surgery day and on the first,3rd,5th and 7th d of surgery(P>0.05).Conclusions The fever rate is higher and the body temperature decreases faster after ventriculoperitoneal shunt.The fever since the third d of surgery is closely related to postoperative intracranial infection,which has a certain predictive significance for postoperative infection,so we should consider anti-infection treatment in time.

关 键 词：术后体温 脑室腹腔分流术 颅内感染 

分 类 号：R651[医药卫生—外科学]