丙泊酚3种用药方案对无痛人工流产术麻醉效果及血流动力学影响  

Influence of 3 different anesthetic regimens on anesthesia effect and hemodynamics of women during painless induced abortion

作　　者：张利亮 张海盛[1] 吴维强[1] 姚泽宇[1] ZHANG Liliang;ZHANG Haisheng;WU Weiqiang;YAO Zeyu(Qinghai Red Cross Hospital Xining,810000)

机构地区：[1]青海红十字医院

出　　处：《中国计划生育学杂志》2019年第12期1645-1647,共3页Chinese Journal of Family Planning

摘　　要：目的:探讨丙泊酚3种配伍方案对无痛人工流产术麻醉效果及其血流动力学的影响。方法:选择2017年9月-2019年4月在本院自愿接受无痛人工流产妇女246例,随机数字表法分为丙泊酚组(丙泊酚+生理盐水)83例、丙泊酚+舒芬太尼组83例和丙泊酚+地佐辛组83例。比较3组麻醉效果和血流动力学指标。结果:总有效率丙泊酚组(83.1%)、丙泊酚+舒芬太尼组(86.7%)和丙泊酚+地佐辛组(96.4%)有差异(P<0.05)。心率(HR)、平均动脉压(MAP)、血氧饱和度(SPO2)水平,诱导前(T0)时点3组无差异(P>0.05);诱导后(Tl)及手术结束时(T2)时点3组低于T0时点,且丙泊酚+地佐辛组>丙泊酚+舒芬太尼组>丙泊酚组(P<0.05)。不良反应率丙泊酚组(28.9%)、丙泊酚+舒芬太尼组(22.9%)、丙泊酚+地佐辛组(10.8%)有差异(P<0.05)。结论:在应用丙泊酚基础上加用地佐辛可提高无痛人工流产术麻醉及镇痛效果,安全性相对较优。Objective:To investigate the influence of 3 different anesthetic regimens on anesthesia effect and hemodynamics of women during painless induced abortion.Methods:246 women who underwent painless induced abortion were included and were randomly divided into group A(83 women received propofol combined with saline),group B(83 women received propofol combined with sufentanil),and group C(83 women received propofol combined with dizocine)from September 2017 to April 2019.The anesthesia effect and hemodynamic indexes of women in the three groups were compared.Results:The total effective rates of women in group A,B,and C were 83.1%,86.7%,and 96.4%,which had significant difference among the three groups(P<0.05).There were no significant different in values of HR,MAP and SPO2 of women in the three groups at T0 time point(P>0.05).The values of HR,MAP and SPO2 of women in the three groups at Tl and T2 time point were significant lower than those of women in the three groups at T0 time point.And the value of HR,MAP or SPO2 of women in group C was the lowest,and that of women in group A was the highest(P<0.05).The adverse reaction rates of women in group A,B,and C were 28.9%,22.9%,and 10.8%,which had significant difference among the three groups(P<0.05).Conclusion:Propofol combined with dizocine for anesthesia during painless induced abortion can improve the effects of anesthetic and analgesic with higher safety.

关 键 词：无痛人工流产术 丙泊酚 舒芬太尼 地佐辛 麻醉效果 血流动力学 

分 类 号：R61[医药卫生—外科学]