不同剂量舒芬太尼对腹部手术患儿全身麻醉诱导期血流动力学及苏醒质量的影响  

Effects of different doses of sufentanil on hemodynamics and recovery quality during induction of general anesthesia in children undergoing short-term and minor operations

作　　者：林占元 刘伟[2] LIN Zhanyuan;LIU Wei(Department of Pediatrics,Yangling Demonstration Zone Hos pital,Yangling,Shaanxi 712100,China;Department of Anesthesiology,Baoji Maternal and Children Health Hospital,Baoji,Shaanxi 721000,China)

机构地区：[1]陕西省杨凌示范区医院儿科,陕西杨凌712100 [2]陕西省宝鸡市妇幼保健院麻醉科,陕西宝鸡721000

出　　处：《检验医学与临床》2019年第24期3603-3605,3609,共4页Laboratory Medicine and Clinic

摘　　要：目的探讨不同剂量舒芬太尼对腹部手术患儿全身麻醉诱导期血流动力学及苏醒质量的影响。方法选取2016年1月至2018年12月杨凌示范区医院收治的90例全身麻醉下择期行腹部手术的患儿为研究对象,按照随机数字表法分为A组(n=30)、B组(n=30)和C组(n=30)。A、B、C组分别给予舒芬太尼0.1、0.2、0.3μg/kg。比较3组血流动力学指标[舒张压(DPB)、收缩压(SBP)、心率(HR)]、自主呼吸恢复时间、苏醒时间、拔管时间、并发症发生率及麻醉深度指数(CSI)。结果3组麻醉前(T0)、出室前(T3)的DBP、SBP、HR水平差异均无统计学意义(P>0.05),3组麻醉后15min(T1)、麻醉后30min(T2)时DBP、SBP、HR水平均显著低于T0时(P<0.05),B组和C组在T1、T2时DBP、SBP、HR水平均显著低于A组(P<0.05);A组和B组自主呼吸恢复时间、苏醒时间及拔管时间均显著短于C组(P<0.05);B组并发症发生率显著低于A组和C组(P<0.05),A组和C组并发症发生率差异无统计学意义(P>0.05)。3组T0、T1、T2、T3时CSI值组间和组内比较差异均无统计学意义(P>0.05)。结论0.2μg/kg舒芬太尼麻醉安全性高,术后苏醒快,值得临床推广应用。Objective To investigate the effects of different doses of sufentanil on hemodynamics and recovery quality during induction of general anesthesia in children undergoing short-term and minor operations.Methods A total of 90 children undergoing elective surgery under general anesthesia who were admitted to the hospital from January 2016 to December 2018 were enrolled.They were divided into group A(n=30),group B(n=30)and group C(n=30)according to random number table method.The three groups were given 0.1,0.2 and 0.3μg/kg sufentanil,respectively.The hemodynamics levels[diastolic blood pressure(DPB),systolic blood pressure(SBP),heart rate(HR)],recovery time of spontaneous breathing,recovery time,extubation time,incidence of complication and cerebral state index(CSI)were compared among the three groups.Results There were no significant differences in DBP,SBP or HR level among the three groups before anesthesia(T0)and before leaving the operating room(T3)(P>0.05).The above indexes at T1 and 30 min after anesthesia(T2)in the three groups were significantly lower than those at T0(P<0.05),the levels of DBP,SBP and HR in group B and group C were significantly lower than those in group A at T1 and T2(P<0.05).There were significant differences in recovery time of spontaneous breathing,recovery time and extubation time among the three groups(P<0.05).The recovery time of spontaneous breathing,recovery time and extubation time of group A and group B were significantly shorter than group C(P<0.05).The incidence of complications of group B was significantly lower than that of group A and group C(P<0.05).There was no significant difference in the incidence of complications between group A and group C(P>0.05).There was no significant difference in CSI values among the three groups at T0,T1,T2 and T3(P>0.05).Conclusion The effects of 0.2μg/kg sufentanil has better effect on children undergoing general anesthesia,which can regain consciousness quickly with relatively higher safety.

关 键 词：全身麻醉 静脉诱导 舒芬太尼 血流动力学 苏醒质量 儿童 

分 类 号：R726[医药卫生—儿科]