盐酸达克罗宁胶浆联合利多卡因咽喉部喷雾应用于食管扩张术患儿的效果  

Observation on the effect of dacronine hydrochloride grouting combined with lidocaine throat spray in children with esophageal dilatation

作　　者：陈晓艳[1] CHEN Xiaoyan(Department of Paediatrics,First People's Hospital of Jingmen,Jingmen,Hubei 448000,China)

机构地区：[1]湖北省荆门市第一人民医院儿科

出　　处：《检验医学与临床》2019年第24期3610-3612,3616,共4页Laboratory Medicine and Clinic

摘　　要：目的观察盐酸达克罗宁胶浆联合利多卡因咽喉部喷雾应用于食管扩张术患儿的效果。方法选择2018年2-11月该院儿科收治的74例行食管扩张术的患儿为研究对象,按照随机数字表法分为两组,每组37例。两组患儿均进行全身麻醉,同时,对照组采用利多卡因咽喉部喷雾,观察组采用盐酸达克罗宁胶浆联合利多卡因咽喉部喷雾;观察两组患儿不同时点血流动力学指标变化、躁动程度、时间指标及不良反应。结果组内比较,两组患儿平均动脉压(MAP)、心率(HR)均显著增高,在即刻手术(T1)时均明显高于麻醉前(T0),差异有统计学意义(P<0.05)。组间比较,观察组患儿T1时的MAP、HR均显著低于对照组患儿(P<0.05),手术结束(T2)时的HR显著低于对照组患儿(P<0.05)。观察组患儿躁动评分显著低于对照组患儿(t=9.385,P<0.001),且观察组患儿苏醒时间显著低于对照组患儿(t=4.064,P<0.001)。观察组总不良反应发生率为10.81%(4/37),显著低于对照组患儿的32.43%(12/37),两组比较,差异有统计学意义(χ~2=5.232,P<0.05)。结论在患儿食管扩张术中应用盐酸达克罗宁胶浆联合利多卡因咽喉部喷雾进行治疗,可较好地稳定血流动力学指标,并可降低躁动程度和减少苏醒时间,不良反应较少,值得临床推广。Objective To observe the effect of dacronine hydrochloride gel combined with lidocaine in the treatment of children with esophageal dilatation.Methods A prospective study was conducted on 74 pediatric children admitted to the hospital for esophageal dilatation from February to November 2018.The patients were divided into two groups according to the order of admission.In which that control group(n=37)was sprayed with lidocaine to the laryngopharynx.The observation group(n=37)accepted dacronine hydrochloride grouting combined with lidocaine throat spray.Hemodynamic changes,the degree of agitation,timing indicators and adverse reactions of the two groups were observed and compared.Results Mean arterial pressure(MAP)and heart rate(HR)at the beginning of the surgery(T1)were significantly higher than that of children before anesthesia(T0,P<0.05).Compared with control group,MAP and HR of observation group at T1 were significantly lower(P<0.05).In addition,HR of the observation group at the finish of the surgery(T2)was significantly lower than that of control group(P<0.05).Restlessness score of children in the observation group were significantly lower than those of the control group(t=9.385,P<0.001).The recovery time of children in the observation group was significantly lower than that in the control group(t=4.064,P<0.001).The rate of adverse reactions of the observation group was 10.81%,which was lower than that of the control group(32.43%),difference was significantly different(χ^2=5.232,P<0.05).Conclusion Dacronine hydrochloride gel combined with lidocaine throat spray in treatment of children with esophageal dilatation could stabilize hemodynamic index,and restlessness,adverse reactions,recovery time could be reduced.

关 键 词：食管扩张术 食管狭窄 盐酸达克罗宁胶浆 

分 类 号：R720.5[医药卫生—儿科]