微针阵列干电极的研究进展  

Research Progress of the Microneedle Array Dry Electrode

作　　者：鲁道欢 李娟 Lu Daohuan;Li Juan(National Engineering Research Center for Healthcare Devices;Guangdong Key Lab of Medical Electronic Instruments and Polymer Material Products,Guangdong Institute of Medical Instruments,Guangzhou 510500,China)

机构地区：[1]广东省医疗器械研究所国家医疗保健器具工程技术研究中心,广州510500 [2]广东省医疗器械研究所广东省医用电子仪器及高分子材料制品重点实验室,广州510500

出　　处：《微纳电子技术》2019年第12期956-964,977,共10页Micronanoelectronic Technology

基　　金：广东省科学院专项资金资助项目(2019GDASYL-0102004,2019GDASYL-0302003,2017GDASCX-0103);广东省科技计划资助项目(2017A070701019,2017A070702010)

摘　　要：生物电信号与人体的健康状况密切相关。如何实现长期监测心电(ECG)、脑电(EEG)、肌电(EMG)和其他各种生物电信号成为当前研究中亟待解决的难题。微针阵列干电极(MNAE)采用刺入式微针电极突破角质层高阻抗特性,有望实现连续、长期、高效的生物电信号采集。结合国内外最新研究进展,在对不同生物电极进行分类和对比的基础上,概述了MNAE在信号采集方面的优势。对MNAE使用过程中影响生物电信号采集质量的主要因素进行了分析,综述了不同种类MNAE的制作工艺、改进技术,同时指出了不同种类MNAE存在的不足,并对以后的发展趋势进行展望。Biopotential signals can directly reflect the health status of the human body.How to realize long-term monitoring electrocardiogram(ECG),electroencephalogram(EEG),electromyogram(EMG)and other various biopotential signals has become an urgent problem to be solved in current research.The microneedle array dry electrode(MNAE)is expected to achieve biopotential signals acquisition continuously,chronically and effectively by using penetrating microneedle electrodes to pierce into the high impedance stratum corneum.The advantages of the signal acquisition during the use of the MNAE are reviewed based on the classification and comparison of different biological electrodes through analyzing the latest research progress at home and abroad.The major influence factors on the quality of biopotential signal acquisition during the use of the MNAE are analyzed.The processes and improvement technologies of different types of MNAEs are reviewed,meanwhile their limitations are pointed out.Finally,the future development trend of MNAEs is prospected.

关 键 词：微针阵列 干电极 生物电信号 采集 阻抗 

分 类 号：TP212.[自动化与计算机技术—检测技术与自动化装置]