围产科产褥期防控产后抑郁的多中心临床研究  

A Multicenter Clinical Study on Prevention and Treatment of Postpartum Depression in Puerperium

作　　者：秦峰 李丽娟[2] 蔡红霞[3] 殷浩 李凤贤 孙佳宁 罗靖 王东燕 腾堃 朱金娜 王月华 陈承美 邓杰芳 张立新 QIN Feng;LI Lijuan;CAI Hongxia;YIN Hao;LI Fengxian;SUN Jianing;LUO Jing;WANG Dongyan;TENG Kun;ZHU Jinna;WANG Yuehua;CHEN Chengmei;DENG Jiefang;ZHANG Lixin(General Research Group,National Maternal Psychosomatic Health Clinic,Beijing 100142,China;Maternal and Child Health Center,Chinese Center for Disease Control and Prevention,Beijing 100098,China;Research Base in Clinic for Maternal Psychosomatic Health,Taihe Hospital,Shiyan Hubei 442000,China;Research Base in Clinic for Maternal Psychosomatic Health,Meihekou Maternal and Child Health Care Hospital,Meihekou Jilin 135000,China;Research Base in Clinic for Maternal Psychosomatic Health,Liqizhuang Community Health Service Center of Xiqing District,Tianjin 300382,China;Research Base in Clinic for Maternal Psychosomatic Health,Debao Maternal and Child Health Care Hospital,Debao Guangxi 533700,China;Research Base in Clinic for Maternal Psychosomatic Health,Maternal and Child Health and Family Planning Service Center of Binhai New Area,Tianjin 300270,China)

机构地区：[1]全国孕产妇心身健康门诊总课题组,北京100142 [2]中国疾病预防控制中心妇幼保健中心,北京100098 [3]十堰市太和医院孕产妇心身健康门诊研究基地,湖北十堰442000 [4]梅河口市妇幼保健院孕产妇心身健康门诊研究基地,吉林梅河口135000 [5]天津市西青区李七庄社区卫生服务中心孕产妇心身健康门诊研究基地,天津300382 [6]德保县妇幼保健院孕产妇心身健康门诊研究基地,广西德保533700 [7]天津市滨海新区妇女儿童保健和计划生育服务中心孕产妇心身健康门诊研究基地,天津300270

出　　处：《中国卫生标准管理》2019年第23期18-21,共4页China Health Standard Management

摘　　要：目的围产和产科门诊在产褥期应用多学科合作模式的生理调控、心理调节、音乐调理(physiological regulation,psychological adjustment,music conditioning,PPM)诊疗系统早期预防产后抑郁的临床效果观察。方法选择2018年11月-12月,在十堰市太和医院等4家医疗机构的孕产妇心身健康门诊研究基地,以产后19~22天的26例产妇为研究对象。采取抽签方式,将受试者随机分为研究组(n=14)及对照组(n=12)。研究组在健康教育基础上,应用PPM进行干预,对照组仅进行健康教育。对于2组产妇的年龄、学历、职业、产妇类型等一般资料进行比较,采用Fisher精确检验。对于治疗前2组产妇自主神经系统(autonomic nervous system,ANS)功能状态数据值及干预3周后2组产妇自主神经系统(ANS)功能状态数据值和爱丁堡产后抑郁量表(EPDS)评分值等呈正态分布的计量资料,采用(x-±s)表示,2组比较采用t检验。结果干预前,研究组产妇ANS数据值(0.2517±0.1047)较对照组(0.2258±0.0929),差异无统计学意义(P>0.05)。2组产妇的年龄、学历、职业、产妇类型构成比比较,差异均无统计学意义(P>0.05)。干预后,研究组产妇ANS数据值(0.5592±0.1792)较对照组(0.2625±0.0879)显著提高,且差异有统计学意义(t=6.588,P=0.000)。干预后,研究组产妇EPDS评分值(4.5833±2.1933)分较对照组(8.0833±4.2310)分显著降低,且差异有统计学意义(t=-2.809,P=0.017)。结论围产和产科门诊在产褥期应用多学科合作模式的PPM临床诊疗系统早期预防产后抑郁成效显著。Objective To observe the clinical effect of physiological regulation,psychological adjustment and music conditioning(physiological regulation,psychological adjustment,music conditioning,PPM)in multidisciplinary cooperative diagnosis and treatment system on the early prevention of postpartum depression in perinatal and obstetric clinics during the puerperium.Methods From November to December 2018,26 puerperants of 19-22 days postpartum were selected from the research base of maternal psychosomatic health clinic in four medical institutions,including Shiyan Taihe Hospital.By drawing lots,the subjects were randomly divided into research group(n=14)and control group(n=12).The control group received only health education.On the basis of health education,the research group was intervened with PPM.The general data including age,educational background,occupation and maternal type were compared between the two groups using Fisher’s exact test.The measurement data of the functional status of the autonomic nervous system(autonomic nervous system,ANS)before treatment and 3 weeks after intervention and Edinburgh Postnatal Depression Scale(EPDS)score in the two groups showing normal distribution were expressed as(x-±s).The comparison between the 2 groups was carried out by t-test.Results Before intervention,no statistically significant difference was found in maternal ANS between the research group(0.2517±0.1047)and the control group(0.2258+0.0929)(P>0.05).Age,educational background,occupation and the constituent ratio of maternal type showed no statistically significant difference between the two groups(P>0.05).After intervention,maternal ANS of the research group(0.5592±0.1792)was significantly higher than that of the control group(0.2625±0.0879),with a statistically significant difference(t=6.588,P=0.000).After intervention,EPDS score of the research group(4.5833±2.1933)was significantly lower than that of the control group(8.0833±4.2310),presenting a statistically significant difference(t=-2.809,P=0.017).Conclusion

关 键 词：产后抑郁 产妇 产褥期 心身障碍 爱丁堡产后抑郁量表 自主神经 PPM 

分 类 号：R714[医药卫生—妇产科学]