象皮粉外掺治疗糖尿病足溃疡虚证的多中心临床观察  

Multicenter clinical observation on treating diabetic foot ulcer of deficiency syndrome with elephant skin powder

作　　者：连晓彤 李茜[2] 黄天一[2] 王刚[2] 李创 邓莉娟 杨光耀 郭娴 张龙[4] 李大勇[5] 杨宝钟[6] 庄百溪[7] 何立刚[8] 何春红 徐晋[10] 王万春[11] 杨博华[2] 刘胜男 李伟红 鞠上[2] LIAN Xiao-tong;LI Qian;HUANG Tian-yi;WANG Gang;LI Chuang;Deng Li-juan;YANG Guang-yao;GUO Xian;ZHANG Long;LI Da-yong;YANG Bao-zhong;ZHUANG Bai-xi;HE Li-gang;HE Chun-hong;XU Jin;WANG Wanchun;YANG Bo-hua;LIU Sheng-nan;LI Wei-hong;JU Shang(Beijing University of Chinese Medicine,Beijing 100029,China;Dongzhimen Hospital,Beijing University of Chinese Mediciney Beijing 100700;Xuanwu TCM Hospital,Beijing 100050;A.Peking University Third Hospital,Beijing 100191;Affiliated Hospital of the Liaoning University of TCM,Shenyang,110032;Dongfang Hospital,Beijing University of Chinese Medicine,Beijing 100078;Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing 100091;He'nan Province Hospital of TCM,Zhengzhou 450000;TCM Hospital of Luoyang,Affiliated to the He'nan University of TCM,Luoyangy 471000;No.2.TCM Hospital of Jiangsu Province,Nanjing 210017;Affiliated Hospital of the Jiangxi University of TCM,Nanchang 330006)

机构地区：[1]北京中医药大学,北京100029 [2]北京中医药大学东直门医院,北京100700 [3]北京市宣武中医医院,北京100050 [4]北京大学第三医院,北京100191 [5]辽宁中医药大学附属医院,沈阳110032 [6]北京中医药大学东方医院,北京100078 [7]中国中医科学院西苑医院,北京100091 [8]河南省中医院,郑州450000 [9]河南中医药大学附属洛阳市中医院,洛阳471000 [10]江苏省第二中医院,南京210017 [11]江西中医药大学附属医院,南昌330006

出　　处：《北京中医药》2019年第11期1088-1092,共5页Beijing Journal of Traditional Chinese Medicine

摘　　要：目的观察象皮粉外掺治疗糖尿病足溃疡虚证患者的临床疗效。方法将2018年6月-2019年6月于北京中医药大学东直门医院周围血管病科等10家单位住院且符合纳入标准的糖尿病足患者分为试验组和对照组,均采用标准化内科基础治疗及创面换药,分别予象皮粉、表皮生长因子外掺,每天1次,观察14天。结果共180例患者完成试验,总有效率分别为95.5%、84.4%。治疗后创面面积、中医证候积分、治疗总费用,试验组均低于对照组(P<0.05)。结论象皮粉外掺治疗糖尿病足溃疡虚证患者有良好的效果。Objective To observe the clinical effect of elephant skin powder in treatment of diabetic foot ulcer.Methods Patients with diabetic foot who were hospitalized in the Department of Peripheral Vascular Diseases of Dongzhimen Hospital and other 9 hospitals from June 2018 to June 2019 and met the inclusion criteria were divided into the experimental group and the control group.Both groups were treated with standardized internal medicine and wound dressing.On this basis,the experimental group and the control group were treated with elephant skin powder and epidermal growth factor respectively for 1 time/d,and observed for 14 days.Results A total of 180 patients completed the trial,90 in the experimental group and 90 in the control group,and the total effective rate was 95.5% and 84.4%respectively.After treatment,the experimental group was superior to the control group in the comparison of the reduction of wound area,the reduction of TCM syndrome scores and total cost(P<0.05).Conclusion Elephant skin powder treatment has a good effect on diabetic foot ulcer with deficiency syndrome.

关 键 词：糖尿病足溃疡 虚证 象皮粉 中医药疗法 

分 类 号：R47[医药卫生—护理学]