NCOA1和RBP4基因多态性与大白猪繁殖性能的关联分析  

Association analysis between genotypes of NCOA1,RBP4 and reproductive performance in Yorkshire sows

作　　者：王斌虎[1] 邱梅玉 赵玉强 谢苏 孙晓梅[1] 来红霞 黄涛[1] WANG Binhu;QIU Meiyu;ZHAO Yuqiang;XIE Su;SUN Xiaomei;LAI Hongxia;HUANG Tao(College of Animal Science and Technolongy,Shihezi University,Shihezi,Xinjiang 832003,China;Xinjiang Chia Tai Food Company Limited,Wujiaqu,Xinjiang 831301,China)

机构地区：[1]石河子大学动物科技学院,新疆石河子832003 [2]新疆正大食品有限公司,新疆五家渠831301

出　　处：《石河子大学学报（自然科学版）》2019年第6期688-693,共6页Journal of Shihezi University(Natural Science)

基　　金：国家国际科技合作项目(2014DFA31840)

摘　　要：目的为了研究NCOA 1和RBP 4基因的多态性对母猪繁殖性能的影响。方法本试验利用PCR-RFLP技术检测试验猪群NCOA 1和RBP 4基因的多态性,并采用最小二乘法对基因多态性与总仔数、活仔数、健仔数、木乃伊数、死胎数等繁殖性状,分别进行单独基因型分析和合并基因型分析。结果对于NCOA 1基因,初产和经产母猪的总产仔数、总活仔数、健仔数和初生窝重都为AB型>AA型,但仅在经产母猪中总产仔数、活仔数差异达到显著水平(P<0.05);对于RBP 4基因,经产母猪的总产仔数、健仔数、初生窝重均表现为AA型>BB型>AB型,且AA型个体的健仔数、初生窝重极显著高于AB型(P<0.01);对于NCOA 1和RBP 4的合并基因型,经产母猪的总产仔数、活仔数、健仔数、死胎数、初生窝重均表现为ABBB型>AAAB型,且ABBB型个体的总产仔数、死胎数极显著高于AAAB型(P<0.01)。结论NCOA 1和RBP 4基因多态性对大白猪的繁殖性能有显著影响,可作为母猪繁殖性能改良的遗传标记。Objective In order to study the effects of the polymorphisms of NCOA 1 and RBP 4 genes on the reproductive performance of sows.Methods PCR-RFLP technique was used to genotype NCOA 1 and RBP 4 genes of sows,and the least squares method was used for association analysis of genotypes and reproductive traits such as total number born(TNB),number born alive(NBA),number born healthy(NBH),number of mummy,number of stillbirth and little weight(LW).Results For NCOA 1 gene,the TNB,NBA,NBH and LW of genotype AB were higher than genotype AA,but only the TNB and NBA in multiparous sows reached significant level(P<0.05).For RBP 4 gene,the TNB,NBA and LW showed a trend that genotype AA higher than BB type and genotype BB higher than AB,and the TNB and LW of genotype AA higher than that of AB very significantly(P<0.01).For the combined genotypes of NCOA 1 and RBP 4,all the TNB,NBA,NBH,stillbirth and LW of genotype ABBB were higher than that of AAAB,only the TNB and stillbirth reached very significant level(P<0.01).Conclusions The genotypes of NCOA 1 and RBP 4 have an effect on the reproduction traits of Yorkshire sows,and can be used as a genetic marker for improving reproductive performance of sows.

关 键 词：猪 NCOA 1基因 RBP 4基因 合并基因型 繁殖性能 

分 类 号：S828.89[农业科学—畜牧学]