抗心磷脂抗体及抗β2糖蛋白I抗体的检测对不明原因流产妇女的的诊断价值  

Diagnostic Value of Anticardioid phospholipid Antibody and Anti-beta2 Glycoprotein I Antibody for Unexplained Abortion in Women

作　　者：韦欣[1] 叶剑锋 龚波 WEI Xin;YE Jian-feng;GNG Bo(Tongrzn Hospital Shanghai Jiaotong University School Of Medicine,Shanghai,200050,China;Shanghai Changning District Maternal And Child Hospital,Shanghai,200051,China)

机构地区：[1]上海交通大学医学院附属同仁医院,上海200050 [2]上海市长宁区妇幼保健院,上海200051

出　　处：《血栓与止血学》2019年第6期901-902,905,共3页Chinese Journal of Thrombosis and Hemostasis

摘　　要：目的观察抗心磷脂抗体(ACA)及抗β2糖蛋白I抗体(Anti-β2-GPI)对不明原因流产妇女的诊断价值。方法采取2016年1月-2018年12月至我院进行不明原因流产妇女100(观察组)进行临床研究。并设对照组100例,所有患者均行aPTT、ACA及Anti-β2-GPI检测。观察两组患者aPTT、ACA、Anti-β2-GPI水平和阳性率。结果观察组患者aPTT、ACA、Anti-β2-GPI水平均明显高于对照组(P<0.05)。结论本文不明原因流产妇女ACA及Anti-β2-GPI升高,表明其流产与抗磷脂综合征相关。Objective The diagnostic value of anticardioid phospholipid antibodies(ACA)and anti-beta2 glycoprotein I antibodies(Anti-beta 2-GPI)for unexplained abortion stompory women was observed.Methods 100(observation group)of women who had unexplained abortions were conducted from January 2016 to December 2018.A control group of 100 cases was set up,and all patients were tested for aPTT,ACA and Anti-beta 2-GPI.aPTT,ACA,Anti-beta 2-GPI levels and positive rates were observed in both groups.Results aPTT,ACA,Anti-beta 2-GPI water were significantly higher than those in the control group(P<0.05)in the observation group.Conclusion The increase of ACA and Anti-beta 2-GPI in women with unexplained abortion indicates that their abortion is related to antiphospholipid syndrome.

关 键 词：抗心磷脂抗体 抗Β2糖蛋白I抗体 抗磷脂综合征 

分 类 号：R446[医药卫生—诊断学]