2009-2016年四川省西昌市女性性工作者HIV感染及相关行为调查  

HIV Infection and High-risk Relative Behaviors Among Female Sex Workers in Xichang in Sichuan From 2009 to 2016

作　　者：宋本莉[1] 张翔[1] 边会珍 殷俊 姜正清 梁姝[2] 邢辉 陈礼 阮玉华[3] SONG Benli;ZHANG Xiang;BIAN Huizhen;YAN Jun;JIANG Zhengqing;LIANG Shu;XING Hui;CHEN Li;YUAN Yuhua(Xichang Center for Disease Control and Prevention,Xichang 615000,Sichuan Province,China;Sichuan center for Disease Control and Prevention,Chengdu 610041,Sichuan Province,China;Division of Virology and Immunology,National Center for AIDS/STD Control and Prevention(NCAIDS),China CDC,Beijing 102206,China;Guangxi Medical University Kaiyuan Langdong Hospital,Naning 530021,Guangxi Province,China)

机构地区：[1]西昌市疾病预防控制中心,四川西昌615000 [2]四川省疾病预防控制中心,成都610041 [3]中国疾病预防控制中心传染病预防控制国家重点实验室,北京102206 [4]广西医大开元埌东医院,南宁530021

出　　处：《预防医学情报杂志》2019年第12期1347-1353,共7页Journal of Preventive Medicine Information

基　　金：国家自然科学基金(项目编号：11471336);“十三五”艾滋病和病毒性肝炎等重大传染病专项(项目编号：2017ZX10201101)

摘　　要：目的了解四川省西昌市2009-2016年女性性工作者(female sex workers,FSW)艾滋病病毒(HIV)感染状况及相关行为情况。方法分别于2009-2010年、2011-2012年、2013-2014年和2015-2016年在西昌市FSW人群中开展4次连续性横断面问卷调查,并抽取5 ml静脉血检测HIV、梅毒和HCV,采用趋势卡方检验分析不同年份及相关行为特征变化趋势,用Logistic模型分析相关危险因素。结果共调查3 211人,HIV、梅毒和HCV感染率分别为0.81%、2.09%和6.14%。2009-2016年女性性工作者HIV(χ^2=0.1,P=0.726)和梅毒感染(χ^2=3.0,P=0.082)变化差异无统计学意义,HCV感染变化呈现上升趋势(χ^2=7.3,P=0.007)。多因素Logistic回归分析结果显示,与HIV感染有统计学意义的变量包括民族(OR=4.40,95%CI:1.84~10.53)、文化程度(OR=2.83,95%CI:1.07-7.49)和近1年被诊断患过性病(OR=3.25,95%CI:1.18~8.93)。结论需继续将女性性工作者纳入当地艾滋病防控的重点人群,同时对少数民族女性性工作者提供针对性宣传教育。Objective To understand the HIV infection and high-risk relative behaviors among female sex workers(FSW) in Xichang, Sichuan from 2009 to 2016. Methods The consecutive crosssectional surveys were conducted to investigate the characteristics of social demography, behaviors using questionnaire and to detect the infection of HIV, syphilis and HCV among female sex workers by extracting 5 ml of venous blood for each subject during 2009-2010, 2011-2012, 2013-2014 and 2015-2016. The study used the trend chi-square test to analyze the change trend of behavior characteristics in different years and the Logistic model to analyze related risk factors.Results A total of 3 211 FSW included in the survey, the incidence rates of HIV, syphilis and HCV were 0.81%, 2.09% and 6.14%, respectively. There were not statistical differences of HIV and HBV infection(P>0.05), but HCV infection showed significant increased(P<0.05) from2009 to 2016. Multi-factor Logistic regression analysis showed that the national(OR=4.40,95%CI:1.84-10.53), education(OR=2.83, 95% CI:1.07-7.49) and STD(OR=3.25, 95% CI:1.18-8.93)were related to the HIV infection. Conclusion The FSW should be kept as the key groups for HIV/AIDS prevention and control, and the targeted publicity and education for minorities FSW should be provided.

关 键 词：女性性工作者 HIV 梅毒 高危行为 

分 类 号：R512.91[医药卫生—内科学]