2型糖尿病患者自我管理行为与认知功能各维度的关系研究  

Relationship between self-management behavior and each dimension of cognitive function in patients with type 2 diabetic mellitus

作　　者：汪璐璐 刘安诺[2] 刘鸿雁[3] 郑红英 孙小红[1] 宫娟[1] 蒋燕[2] WANG Lu-lu;LIU An-nuo;LIU Hong-yan;ZHENG Hong-ying;SUN Xiao-hong;GONG Juan;JIANG Yan(The First Affiliated Hospital of Anhui Medical University,Hefei,Anhui 230022,China;School of Nursing,Anhui Medical University,Hefei,Anhui 230032,China;The Third People's Hospital of Hainan Province,Sanya,Hainan 572000,China)

机构地区：[1]安徽医科大学第一附属医院,安徽合肥230022 [2]安徽医科大学护理学院,安徽合肥230032 [3]海南省第三人民医院,海南三亚572000

出　　处：《实用预防医学》2020年第1期1-4,共4页Practical Preventive Medicine

基　　金：2018年安徽省自然科学基金项目(1808085MH277)

摘　　要：目的探讨2型糖尿病(type 2 diabetic mellitus,T2DM)患者认知功能现状及其与自我管理行为之间的相关性。方法选取2016年1-10月合肥市某三甲医院内分泌科住院的149例T2DM患者为研究对象,采用一般资料调查表、长沙版蒙特利尔认知评估量表和糖尿病自我管理活动问卷进行调查,应用t检验、χ^2检验及多因素logistic回归分析T2DM患者轻度认知损害(mild cognitive impairment,MCI)患病现状、影响因素及自我管理行为与认知功能各维度的关系。结果T2DM患者MCI的患病率为40.94%,年龄、合并脑梗塞是MCI的危险因素(OR=4.38、5.25),受教育程度、喝茶和自我管理行为是MCI的保护因素(OR=0.52、0.29、0.03)。自我管理行为中饮食正向预测视空间/执行、命名、注意功能和认知功能总分(β=0.16、0.20、0.29、0.12),运动正向预测定向功能(β=0.25),遵医嘱服药正向预测视空间/执行、延迟记忆和定向功能(β=0.13、0.16、0.15)。结论T2DM患者自我管理行为与认知功能之间存在相关性,临床医护工作者可通过对T2DM患者自我管理行为进行针对性地预防、干预,延缓T2DM患者MCI的发生、进展。Objective To explore the current status of cognitive function and its correlation with self-management behavior in patients with type 2 diabetic mellitus(T2DM).Methods One hundred and forty-nine patients with T2 DM hospitalized in department of endocrinology,a tertiary hospital in Hefei city from January to October in 2016 were selected to serve as the research subjects.All of the patients were assessed using general information questionnaire,Montreal Cognitive Assessment Scale(Changsha Version)and the Summary of Diabetes Self-care Activities Questionnaire.The t-test,χ^2 test and multivariate logistic regression analysis were used to analyze the prevalence of mild cognitive impairment(MCI),the influencing factors and the relationship between self-management behavior and each dimension of cognitive function.Results The prevalence rate of MCI among the patients with T2 DM was 40.94%.Age(OR=4.38),complicating with cerebral infarction(OR=5.25)were risk factors for MCI,while educational background(OR=0.52),drinking tea(OR=0.29)and self-management behavior(OR=0.03)were protective factors for MCI.Among self-management behavior,diet positively predicted visual space/executive function(β=0.16),naming(β=0.20),attention(β=0.29)and the total score of cognitive function(β=0.12),exercise positively predicted orientation(β=0.25),and prescribed medication positively predicted visual space/executive function(β=0.13),delayed memory(β=0.16)and orientation(β=0.15).Conclusions There is a correlation between self-management behavior and cognitive function in patients with T2 DM.Targeted prevention and intervention based on self-management behavior of the patients with T2 DM should be made in clinical practice so as to delay the occurrence and development of MCI.

关 键 词：糖尿病 2型 自我管理行为 轻度认知损害 

分 类 号：R587.1[医药卫生—内分泌]