植物源驱避剂孟二醇对白纹伊蚊的实验室药效研究  

Repellent activity of plant-derived P-menthane-3,8-diol to Aedes albopictus in laboratory

作　　者：田野[1] 陈红娜[1] 刘大鹏[1] 刘慧[1] 张育富[1] 吴治明[1] 杨维芳[1] 张爱军[1] 褚宏亮[1] 周明浩[1] TIAN Ye;CHEN Hong-na;LIU Da-peng;LIU Hui;ZHANG Yu-fu;WU Zhi-ming;YANG Wei-fang;ZHANG Ai-jun;CHU Hong-liang;ZHOU Ming-hao(Jiangsu Provincial Center for Disease Control and Prevention,Nanjing 210009,China)

机构地区：[1]江苏省疾病预防控制中心

出　　处：《中华卫生杀虫药械》2019年第6期546-548,共3页Chinese Journal of Hygienic Insecticides and Equipments

基　　金：江苏省流行病学重点学科项目(编号:ZDXKA2016008);国家“十三五”科技重大专项课题(编号:2017ZX10303404);江苏省青年医学人才项目(编号:QNRC2016544)

摘　　要：目的观察不同浓度的植物源性驱避剂孟二醇对白纹伊蚊的实验室药效,并与避蚊胺进行比较,评价其驱蚊效果。方法参照国家标准GB/T 13917.9-2009试验方法,分别对不同浓度的孟二醇和避蚊胺进行实验室药效测试并进行评价。结果孟二醇对白纹伊蚊的驱避效果随浓度的升高而增强。15%孟二醇的有效保护时间超过4 h[(4.33±0.82)h],达到国家驱避剂登记的B级标准。各浓度孟二醇的驱避效果分别低于相同浓度的避蚊胺(P<0.05),20%孟二醇与10%避蚊胺的驱避效果相当(P>0.05)。结论孟二醇对白纹伊蚊具有较好的驱避效果,可作为防蚊虫叮咬的植物源性驱避剂推广应用。Objective To observe the different concentrations of p-menthane-3,8-diol(PMD)against Aedes albopictus and compare it with N,N-diethyl-m-toluamide(DEET)to evaluate its repellent effect.Methods Referring to the national standard GB/T 13917.9-2009 test method,the laboratory efficacy of PMD and DEET at different concentrations was tested and evaluated.Results PMD bettered repellent effect to Aedes albopictus with the increase of concentrations.The protective time of 15%PMD was more than 4 hours[(4.33±0.82)h],reaching the grade B standard of national repellent registration.The repellent effect of each concentration of PMD was lower than that of the same concentration of DEET(P<0.05),and 20%PMD showed efficacy similar to 10%DEET(P>0.05).Conclusion PMD showed good repellent effect to Aedes albopictus.It can be used as a qualified botanical repellent to prevent mosquito bites.

关 键 词：植物源驱避剂 孟二醇 避蚊胺 白纹伊蚊 有效保护时间 

分 类 号：R184.31[医药卫生—流行病学] S482.38[医药卫生—公共卫生与预防医学]