新生儿垂体柄中断综合征一例  

Pituitary stalk interruption syndrome in newborn:a case report

作　　者：石卉 陶莉 赵宁 Shi Hui;Tao Li;Zhao Ning(Department of Neonatology,Guangzhou Women and Children's Medical Center,Guangzhou 510120,China;Neonatal Intensive Care Unit,Guangzhou Women and Children's Medical Center,Guangzhou 510120,China)

机构地区：[1]广州市妇女儿童医疗中心新生儿科,510120 [2]广州市妇女儿童医疗中心新生儿重症监护病房,510120

出　　处：《中华围产医学杂志》2019年第12期891-893,共3页Chinese Journal of Perinatal Medicine

摘　　要：本文报道了1例女婴,因其母亲过期妊娠(停经43周+2)行剖宫产娩出,出生体重2950 g。生后约14 h出现颜面发绀,血糖1.4 mmol/L。入院后查游离三碘甲状腺原氨酸、游离四碘甲状腺素、促甲状腺激素、生长激素、胰岛素样生长因子-1明显降低,经头颅MRI检查确诊为垂体柄中断综合征,予氢化可的松、左旋甲状腺素片替代治疗,临床症状好转、血糖稳定后出院。患儿生后6及10个月时随访血糖不稳定、甲状腺功能低下,1岁3个月随访体格发育落后。This study reported a postterm female infant born at 43+2 weeks of gestation via cesarean section with a birth weight of 2950 g.Cyanosis was presented around 14 h after birth.Laboratory test results showed that the blood glucose was 1.4 mmol/L and the levels of free triiodothyronine(FT3),free tetraiodothyronine(FT4),thyrotropin(TSH),growth hormone(GH)and insulin-like growth factor-1(IGF-1)were significantly reduced.Cranial MRI confirmed the diagnosis of pituitary stalk interruption syndrome.The baby girl was treated with hydrocortisone and levothyroxine and discharged following clinical symptoms improvement and blood glucose normalization.Follow-up data showed unstable blood glucose and hypothyroidism at six and 10 months after birth and growth retardation at 15 months.

关 键 词：垂体疾病 低血糖症 甲状腺功能减退症 婴儿 新生 

分 类 号：R71[医药卫生—妇产科学]