成人头面部带状疱疹早期治疗前后皮损、神经痛及血压变化研究  

Skin lesion,neuralgia and blood pressure before and after early formal treatment on herpes zoster of the head and face inadults:a quantitative study

作　　者：张静[1] 范文葛[1] 王玲[1] 魏梅[1] 赵军[1] 陶晓瑜[1] 薛峤[1] 丁浩[1] Zhang Jing;Fan Wenge;Wang Ling;Wei Mei;Zhao Jun;Tao Xiaoyu;Xue Qiao;Ding Hao(Department of Dermatology,Changshu No.1 People's Hospital,Changshu Hospital Affiliated to Soochow University,Changshu 215500,China)

机构地区：[1]苏州大学附属常熟市第一人民医院皮肤科,215500

出　　处：《中华医学美学美容杂志》2019年第6期491-495,共5页Chinese Journal of Medical Aesthetics and Cosmetology

摘　　要：目的探讨高血压患者与非高血压患者头面部带状疱疹早期规范治疗前后皮损、神经痛及血压变化。方法收集2015年6月至2018年5月江苏省常熟市第一人民医院皮肤科住院带状疱疹患者104例,其中高血压46例为高血压组,无高血压58例为非高血压组。比较两组治疗前后皮损、疼痛数字评分法(NRS)评分及血压变化。结果共99例完成治疗,高血压组45例中男25例,女20例,年龄35~71(52.40±12.51)岁;非高血压组54例中男30例,女24例,年龄36~75(52.62±12.67)岁。两组患者治疗后皮损控制时间、好转时间、愈合时间比较,差异无统计学意义(t=0.457、0.607、1.399,P>0.05)。两组治疗前NRS评分差异无统计学意义(t=0.009,P>0.05)。两组治疗后NRS评分较治疗前下降,同组治疗前后比较,差异有统计学意义(F=151.130、181.444,P<0.05)。两组治疗后NRS评分比较,差异无统计学意义(Z=-0.032、-0.154、-0.149、-0.426,P>0.05)。高血压组治疗前血压升高62.22%,治疗后血压较治疗前下降,治疗前后比较,差异有统计学意义(P<0.05)。非高血压组治疗前血压升高5.56%,治疗后血压较治疗前下降,但差异无统计学意义(P>0.05)。结论带状疱疹发生时血压可升高,有高血压病史者明显。带状疱疹早期规范治疗后,皮损愈合,神经痛减轻,血压可恢复正常。高血压病史及治疗前血压升高对带状疱疹皮损愈合及神经痛减轻无影响.Objective To observe the changes of skin lesion,neuralgia and blood pressure in hypertension patients and non-hyperension patients before and after the early formal treatment on herpes zoster in the head and face.Methods Clinical data were collected from June 2015 to May 2018 in the Department of Dermatology,the First People's Hospital,Changshu,Jiangsu province.In 104 cases of hospitalized patients with herpes zoster,46 cases had high blood pressure(hypertension group);58 cases did not have high blood pressure(non-hypertension group).The skin lesion,numerical rating scale(NRS)and blood pressure changes were compared between the two groups before and after treatment.Results A total of 99 patients completed treatment;45 cases in the hypertensive group included 25 males,20 females,aged 35 to 71(52.40±12.51)years;54 cases in the non-hypertensive group included 30 males and 24 females,aged 36 to 75(52.62±12.67)years.There was no statistically significant difference in the time of control,improving and healing of skin lesion(t=-0.457,-0.607 and 1.399,P>0.05).There was no statistically significant difference in NRS between the two groups before treatment(t=-0.009,P=0.993>0.05).After treatment,the NRS of both groups decreased compared with those before treatment,and the difference was statistically significant(F=151.130,181.444,P<0.05).There was no significant difference in NRS between the two groups after treatment(Z=-0.032,-0.154,-0.149 and-0.426,P>0.05).In the hypertension group,the rate of blood pressure increase before treatment was 62.22%,and the blood pressure decreased after treatment compared with that before treatment.The difference was statistically significant(P<0.05).In the non-hypertension group,the rate of increase of blood pressure before treatment was 5.56%,and the blood pressure after treatment was lower than before treatment.The difference was not statistically significant before and after treatment(P>0.05).Conclusions Blood pressure can be increased when herpes zoster occurs.After early formal treat

关 键 词：带状疱疹 皮肤表现 高血压 神经痛 治疗 

分 类 号：R75[医药卫生—皮肤病学与性病学]