倍舒痕硅凝胶和积雪苷霜治疗内眦赘皮矫正术后瘢痕增生的疗效  

Clinical effects of Dermatix Ultra silica gel and asiaticoside cream on hyperplastic scar tissue in patients after epicanthoplasty

作　　者：高侠[1] 林金德[1] 孙露[1] 任烨 Gao Xia;Lin Jinde;Sun Lu;Ren Ye(Department of Plastic and Aesthetic Surgery,Friendship Plastic Surgery Hospital,Nanjing Medical University,Nanjing 210009,China)

机构地区：[1]南京医科大学友谊整形外科医院整形科,210009

出　　处：《中华医学美学美容杂志》2019年第6期508-511,共4页Chinese Journal of Medical Aesthetics and Cosmetology

摘　　要：目的观察内眦赘皮矫正术后外用倍舒痕硅凝胶或积雪苷霜对瘢痕组织的疗效。方法2016年3月至2017年3月,南京医科大学友谊整形外科医院整形科将90例[男5例,女85例,年龄(28.1±6.95)岁]内眦赘皮矫正术后患者分为对照组、倍舒痕硅凝胶组、积雪苷霜组3组,每组30例。分别于术后4周和12周,进行患者和观察者瘢痕评价量表(POSAS)评估。随访6个月,对患者满意度进行判定。结果术后4周和12周,倍舒痕硅凝胶组和积雪苷霜组POSAS评分明显低于对照组,差异有统计学意义(均P<0.05)。术后4周,倍舒痕硅凝胶组POSAS评分低于积雪苷霜组,差异有统计学意义(P<0.05),术后12周两组POSAS评分差异无统计学意义(P>0.05)。随访6个月,倍舒痕硅凝胶组和积雪苷霜组患者满意度均较对照组高(P<0.05);倍舒痕硅凝胶组患者满意度较积雪苷霜组高(P<0.05)。结论倍舒痕硅凝胶和积雪苷霜对内眦赘皮矫正术后瘢痕组织均有较好的抑制增生作用。倍舒痕硅凝胶在瘢痕愈合早期疗效优于积雪苷霜。Objective To observe the clinical efficacy of Dermatix Ultra silica gel and asiaticoside cream for the treatment or repair of scar hyperplasia which was external used in internal corner incision of patients after the internal canthus correction operation.Methods A total of 90 patients were randomly chosen and divided into three groups.All patients with epicanthus were treated with the same internal canthus correction method by one doctor.There were 30 patients in each group:30 cases in the control group were treated without any medication,and the postoperative incision healed naturally;30 cases were treated with Dermatix Ultra silica gel;30 cases were treated with asiaticoside cream.Patient and observer scar assessment scale(POSAS)was used as the end points to evaluate the clinical efficacy of Dermatix Ultra silica gel and asiaticoside cream 4 weeks and 12 weeks after the operation.The satisfactory degree from all the patients were collected after 6 months follow-up and we compared the scores of three groups.Results Compared with the control group,the POSAS scores in Dermatix Ultra silica gel group and asiaticoside cream group were low(P<0.05)at 4 weeks and 12 weeks after operation.At 4 weeks after operation,the POSAS score in Dermatix Ultra silica gel group was lower than that in the asiaticoside cream group(P<0.05).At 12 weeks after operation,there was no significant difference in POSAS score between Dermatix Ultra silica gel group and asiaticoside cream group(P>0.05).Follow-up for 6 months,the satisfaction degree of patients in Dermatix Ultra silica gel group and asiaticoside cream group was higher than in the control group(P<0.05);the satisfactory degree of patients in Dermatix Ultra silica gel group was higher than that in asiaticoside cream group(P<0.05).Conclusions Dermatix Ultra silica gel and asiaticoside cream have good clinical effects in repair of scar tissue after the epicanthoplasty.Dermatix Ultra silica gel is better than asiaticoside cream in scar early improvement.

关 键 词：瘢痕 增生 积雪苷霜 硅凝胶 内眦赘皮 

分 类 号：R47[医药卫生—护理学]