海洋中药厚藤的质量标准研究  

Study on Quality Standard of Traditional Marine Chinese Medicine Ipomoea pes-caprae

作　　者：冯小慧 韦棪婷 邓家刚[1,2,3] 谢滟 徐炜杰[1,2,3] 侯小涛 FENG Xiaohui;WEI Yanting;DENG Jiagang;XIE Yan;XU Weijie;HOU Xiaotao(Guangxi University of Chinese Medicine,Nanning,Guangxi,530200,China;Guangxi Key Laboratory of Efficacy Study on Chinese Materia Medicia,Nanning,Guangxi,530200,China;Guangxi Collaborative Innovation Center for Research on Functional Ingredients of Agricultural Residues,Nanning,Guangxi,530200,China)

机构地区：[1]广西中医药大学,广西南宁530200 [2]广西中药药效研究重点实验室,广西南宁530200 [3]广西农作物废弃物功能成分研究协同创新中心,广西南宁530200

出　　处：《广西科学》2019年第5期503-510,共8页Guangxi Sciences

基　　金：广西科技计划项目（桂科AD17195025）;2018广西一流学科建设项目重点课题（2018XK043）资助

摘　　要：为了建立海洋中药厚藤(Ipomoea pes-caprae(Linn.)Sweet)的质量标准,本研究采用薄层色谱法,以咖啡酸为对照品,对厚藤进行定性鉴别;采用高效液相色谱法,对厚藤中绿原酸、咖啡酸、异槲皮苷、异绿原酸B、异绿原酸A、异绿原酸C等6个成分进行含量测定。结果显示,本研究建立的厚藤薄层色谱鉴别法,色谱图斑点清晰,分离度好,专属性强;检测得到10批不同产地厚藤中6个成分的含量范围。表明本研究建立的质量标准可有效控制厚藤的质量。This study was conducted to establish the quality standard of marine Chinese medicine Ipomoea pescapraeI.pomoea pes-caprae was identified with caffeic acid as the reference substance by TLC.The content of six components such as caffeic acid,chlorogenic acid,isoquercitrin,isochlorogenic acid B,I sochlorogenic acid A,and isochlorogenic acid C in Ipomea pes-caprae was determined by high performance liquid chromatography.A TLC method for identification of Ipomoea pes-caprae was established.The chromatograms for Ipomoea pes-caprae were clear,the resolution was good,and the specificity was strong.The content range of 6 components in 10 batches of different Ipomoea pes-caprae was detected.The quality standards established in this study can effectively control the quality of Ipomoea pes-caprae.

关 键 词：厚藤 海洋中药 质量标准 TLC HPLC 

分 类 号：R282.77[医药卫生—中药学]