基于近红外光谱在皮瓣移植术后的监测系统  

Monitoring systems for skin flap transplantation based on near infrared spectroscopy

作　　者：张锦龙[1] 辛明 樊琳琳 张峰[2] 员琳 韩笑笑 杨濠琨 ZHANG Jinlong;XIN Ming;FAN Linlin;ZHANG Feng;YUAN Lin;HAN Xiaoxiao;YANG Haokun(National Demonstration Center for Experimental Physics and Electronics Education,School of Physics and Electronics,Henan University,Kaifeng 475004,China;School of Electronic Engineering,Beijing University of Posts and Telecommunications,Beijing 100876,China)

机构地区：[1]河南大学物理与电子学院物理与电子国家级实验教学示范中心,开封475004 [2]北京邮电大学电子与工程学院,北京100876

出　　处：《激光技术》2020年第1期91-95,共5页Laser Technology

基　　金：国家自然科学基金资助项目(61675063);河南省科技发展计划资助项目(162102210021)

摘　　要：皮下组织血氧参量是反映皮瓣移植术后皮瓣存活状况的重要依据。为了无创、连续、实时地监测皮肤组织氧饱和度,采用近红外光谱法进行了理论分析和实验验证,提出了一种电流-电压(I-V)转换思路并搭建了测量系统。利用该系统进行了稳定性验证实验、前臂静脉阻断模拟皮瓣血管栓塞实验。结果表明,不同人体、不同部位的组织氧饱和度存在微小差异,差异幅度均在0.05左右;静脉阻断下系统组织氧参量发生显著改变,最大降幅0.25。该系统具有较高灵敏度,能够连续测量组织氧饱和度参量、反映组织氧变化趋势,可以为临床检测术后皮瓣血氧运输状态提供重要参考。Oxygen parameters of subcutaneous tissue are the important basis to reflect the survival of skin flaps after skin flap transplantation.In order to monitor the oxygen saturation of skin tissue noninvasively,continuously and in real time,theoretical analysis and experimental verification were carried out by near infrared spectroscopy.A current-voltage(I-V)conversion method was proposed and a measurement system was built.The system was used to validate the stability and simulate the vascular embolization of forearm vein occlusion flaps.The results show that,there is a slight difference in tissue oxygen saturation in different parts of different human bodies,it is about 0.05.Under venous occlusion,oxygen parameters of the system tissue change significantly.The maximum decrease is 0.25.The system has high sensitivity.It can continuously measure tissue oxygen saturation parameters and reflect the trend of tissue oxygen change.It can provide important reference for clinical detection of oxygen transport status of skin flaps after operation.

关 键 词：生物光学 组织氧饱和度 近红外光谱 皮瓣移植 术后监测 

分 类 号：R318[医药卫生—生物医学工程]