MR组织追踪技术评价孤立性左心室心肌致密化不全及扩张型心肌病应变  

MR Tissue Tracking in Assessing Isolated Left Ventricular Non-compaction and Dilated Cardiomyopathy Strain

作　　者：姜孟春 曾牧 郭杨钰 谢幸芷 邹志敏 刘辉[1] JIANG Mengchun;ZENG Mu;GUO Yangyu;XIE Xingzhi;ZOU Zhimin;LIU Hui(Department of Radiology,Second Xiangya Hospital of Central South University,Changsha 410011,China)

机构地区：[1]中南大学湘雅二医院放射科

出　　处：《中国医学影像学杂志》2019年第10期755-760,765,共7页Chinese Journal of Medical Imaging

基　　金：国家自然科学基金（81701660）

摘　　要：目的探讨MR组织追踪技术(MR-TT)定量分析孤立性左心室心肌致密化不全(ILVNC)及扩张型心肌病(DCM)心肌应变差异的价值。资料与方法回顾性分析临床确诊的行MR检查的ILVNC患者(42例)、DCM患者(40例)及正常者(45例,对照组)的MR资料,应用CVI42软件测量左心室径向应变(RS)、周向应变(CS)、纵向应变(LS),定义心尖部应变与基底部应变的差值为基底部-心尖部应变梯度,进行统计学分析。结果ILVNC组及DCM组整体及各水平RS、CS、LS均低于对照组(P<0.001)。ILVNC组心尖部CS低于DCM组,整体及基底部LS高于DCM组(P<0.05)。DCM组及对照组心尖部CS、LS高于基底部(P<0.05),ILVNC组心尖部与基底部CS、LS差异无统计学意义(P>0.05)。ILVNC组基底部-心尖部LS梯度明显低于DCM组及对照组[分别为(-1.1±2.3)%、(-3.4±1.3)%、(-4.2±1.1)%,P<0.001],ILVNC组CS梯度为正值(0.3±2.0)%。结论ILVNC及DCM患者左心室心肌整体及各水平应变均显著减低,但变化模式不同;MR-TT技术能定量评估这种差异。Purpose To explore the value of MR tissue tracking(MR-TT)in quantitative analysis of isolated left ventricular noncompaction(ILVNC)and dilated cardiomyopathy(DCM).Materials and Methods MR data of clinically confirmed ILVNC patients(42 cases)receiving MR examination,DCM patients(40 cases)and normal subjects(45 cases,control group)were analyzed retrospectively,and CVI42 software was used to measure the left ventricular radial strain(RS),circumferential strain(CS)and longitudinal strain(LS),the difference between the apical and basal strain was defined as the base-apical strain gradient.Results The global and regional RS,CS and LS both in ILVNC group and DCM group were lower than those in the control group(P<0.001).The apical CS in ILVNC group was lower than that in DCM group,and the global and basal LS in ILVNC group were higher than those in DCM group(P<0.05).The apical CS and LS were higher than those in the basal part in the DCM group and the control group(P<0.05),the difference between the apical and basal CS and LS was not statistically significant(P>0.05).The basal-apical LS gradient of the ILVNC group was obviously lower than that of the DCM group and the control group[(-1.1±2.3)%,(-3.4±1.3)% and(-4.2±1.1)%,respectively,P<0.001],and the CS gradient was positive in ILVNC group(0.3±2.0)%.Conclusion The global and regional strain of myocardium of left ventricle in ILVNC and DCM patients are significantly reduced,but the change pattern is different.MR-TT can evaluate this difference quantitatively.

关 键 词：孤立性心室肌致密化不全 心肌病 扩张型 磁共振成像 图像处理 计算机辅助 心肌 心室功能 左 

分 类 号：R542.2[医药卫生—心血管疾病] R445.2[医药卫生—内科学]