原发性肝癌患者介入术后应用动脉压迫器止血相关不良事件的危险因素分析  

Analysis of risk factors of adverse events related to hemostasis with arterial compressor in patients with primary liver cancer after interventional operation

作　　者：张晓丽 于苹苹 Zhang Xiaoli;Yu Pingping(The Second Department of Radiation Intervention,Oriental Hepatobiliary Surgery Hospital,Shanghai 200438)

机构地区：[1]东方肝胆外科医院放射介入二科

出　　处：《护士进修杂志》2019年第24期2220-2223,共4页Journal of Nurses Training

摘　　要：目的探讨影响原发性肝癌患者介入术后应用动脉压迫器止血时压迫相关不良事件的危险因素。方法收集2015年10月-2017年4月我院肝动脉介入治疗的1 203例患者的病史资料,根据实验室检查结果,将患者分为相关不良事件组和无相关不良事件组。分析可能影响原发性肝癌患者介入术后应用动脉压迫器止血时压迫相关不良事件的危险因素。结果 (1)单因素分析结果显示,年龄、性别、体质量、BMI、糖尿病、慢性呼吸系统疾病及凝血酶原异常情况是影响原发性肝癌患者介入术后应用动脉压迫器止血时压迫相关不良事件的危险因素,差异有统计学意义(P<0.05)。(2)多因素Logistic分析结果显示,BMI≥25、合并糖尿病及凝血酶原时间异常是影响原发性肝癌患者介入术后应用动脉压迫器止血时压迫相关不良事件的独立影响因素,其中合并糖尿病患者出现压迫相关不良事件的风险为无糖尿病患者的2.4倍(OR=2.426,95%CI=1.749~4.045,P<0.05)。结论肝癌介入治疗术后应用动脉压迫器止血时,应注意对肥胖、合并糖尿病或凝血功能异常患者压迫相关不良事件的预防及管理。Objective To explore the risk factors of adverse events during mechanical compression for people undergoing femoral arterial puncture. Methods 1325 patients undergoing hepatic artery interventional therapy from October 2015 to April 2017 in our department were enrolled in this retrospective analysis. The medical history data and pre-treatment laboratory results were collected. A logistic review was used to analyze the influence of preoperative factors on the incidence of adverse events. Results(1) Single factor analysis results show that age, sex, body mass, BMI, diabetes mellitus, chronic respiratory diseases and prothrombin abnormalities are the risk factors of compression related adverse events in patients with primary liver cancer after interventional therapy. There was significant difference( P<0.050). Multivariate analysis showed that BMI≥25, diabetes mellitus, and prolonged prothrombin time were independent factors influencing compression-related adverse events. Among that, diabetes is associated with an increased 2.4 times risk of compression-related adverse events(OR=2.426,95%CI 1.749~4.045,P<0.05). Conclusion Additional attention should be paid to the prevention and management for the elder, diabetes mellitus or coagulopathy undergoing mechanical compression hemostasis after interventional therapy.

关 键 词：原发性肝癌 介入手术 动脉压迫止血器 危险因素 护理 

分 类 号：R472[医药卫生—护理学] R735.7[医药卫生—临床医学]