不同地区藏药达乌里秦艽MEKC指纹图谱研究  

Study of MEKC Fingerprint of the Tibetan Medicine Gentiana dahurica Fisch from Different Areas

作　　者：李成思 卢永昌 王志波 张军文 白雪 宋仁君 LI Cheng-si;LU Yong-chang;WANG Zhi-bo;ZHANG Jun-wen;BAI Xue;SONG Ren-jun(College of Pharmacy,Qinghai Nationalities University,Xining 810007,China;Key Laboratory of Plant Resources Chemical Research of Qinghai-Tibet Plateau in Qinghai Province,Xining 810007,China;Key Laboratory of Pharmaceutical Analysis in Qinghai Province,Xining 810007,China)

机构地区：[1]青海民族大学药学院,西宁810007 [2]青海省青藏高原植物化学研究重点实验室,西宁810007 [3]青海省药物分析重点实验室,西宁810007

出　　处：《西南大学学报（自然科学版）》2019年第11期25-29,共5页Journal of Southwest University(Natural Science Edition)

基　　金：国家自然科学基金项目(81760783);青海省重点实验室发展专项(2017-ZJ-Y19)

摘　　要：在最佳的毛细管电泳条件下建立达乌里秦艽指纹图谱.实验选择胶束毛细管电泳法,测得的指纹图谱具有11个共有峰.通过共有峰的相对保留时间和峰面积,可以衡量药材的质量及其真伪.实验方法的稳定性、精密度、重现性良好,说明实验方法准确可靠,可以为达乌里秦艽质量控制研究提供方法和思路.An MEKC(micellar electrokinetic chromatographic)fingerprint of Gentiana dahurica Fisch was established under optimal capillary electrophoresis conditions.The fingerprint had 11 common peaks.The relative retention time and peak area of the common peaks were used to measure the quality and authenticity of medicinal materials.This experimental method was shown to have good stability,precision and reproducibility and,therefore,is accurate and reliable and is recommended for quality control of G.dahurica Fisch.

关 键 词：达乌里秦艽 胶束毛细管电泳 指纹图谱 相似度 

分 类 号：Q969.426.5[生物学—昆虫学]