中药膏方联合穴位埋线治疗支气管哮喘缓解期临床观察  

Clinical observation on the treatment of bronchial asthma in remission period with traditional Chinese medicine soft extract and acupoint catgut embedding

作　　者：王品[1] 王淑英[1] 冯文杰[1] 孙文静 王虹 WANG Pin;WANG Shuying;FENG Wenjie(Department of Lung Disease,Qinhuangdao Hospital of Traditional Chinese Medicine,Qinhuangdao,Hebei 066000)

机构地区：[1]河北省秦皇岛市中医医院肺病科

出　　处：《河北中医》2019年第10期1475-1479,1485,共6页Hebei Journal of Traditional Chinese Medicine

基　　金：河北省秦皇岛市科学技术局2018年度市级科技计划自筹经费项目(编号:201805A095)

摘　　要：目的观察中药膏方联合穴位埋线治疗支气管哮喘(以下简称哮喘)缓解期的临床效果。方法将110例哮喘缓解期患者按照随机数字表法分为2组。对照组55例予沙美特罗替卡松粉吸入剂治疗,治疗组55例在对照组治疗基础上加膏方联合穴位埋线治疗,2组均治疗3个月。比较2组治疗前及治疗1个月、3个月时肺功能指标第1 s用力呼气容积占预计值百分比(FEV1%)、用力肺活量占预计值百分比(FVC%)、呼气流量峰值占预计值百分比(PEF%),炎症相关指标呼出气一氧化氮(FeNO)、外周血嗜酸性粒细胞百分比,哮喘控制测试(ACT)评分;比较2组治疗前后哮喘主要症状、体征(喘息、胸闷、咳嗽、咯痰、哮鸣音)评分。结果治疗1、3个月时,2组FEV1%、FVC%、PEF%均较本组治疗前明显升高(P<0.05),且治疗组高于对照组同期(P<0.05)。治疗3个月后,2组FeNO、嗜酸性粒细胞百分比均较本组治疗前降低(P<0.05),且治疗组均低于对照组同期(P<0.05)。治疗3个月后,2组ACT评分均较本组治疗前升高(P<0.05),且治疗组高于对照组(P<0.05)。治疗3个月后,治疗组喘息、胸闷、咳嗽、咯痰、哮鸣音评分均较本组治疗前降低(P<0.05);对照组各症状、体征评分无明显变化(P>0.05)。结论中药膏方联合穴位埋线可以改善哮喘缓解期患者肺功能,降低气道炎性反应,缓解症状。Objective To observe the effect of traditional Chinese medicine soft extract combined with acupoint catgut embedding in the treatment of asthma in remission period. Methods 110 asthmatic patients in remission period were divided into two groups according to random number table method. 55 cases in control group were treated by salmeterol and ticasone powder inhalation. 55 cases in treatment group were treated by soft extract combined with acupoint catgut embedding on the basis of the control group. Both groups were treated for 3 months. The pulmonary function indexes such as the first second forced expiratory volume(FEV1%), forced vital capacity(FVC%), peak expiratory flow(PEF%), inflammatory related index exhaled nitric oxide(FeNO), percentage of eosinophils in peripheral blood, and asthma control test(ACT) scores before and after treatment were compared before treatment, at one month and three months after treatment were compared. The main symptoms and signs of asthma(pant, chest distress, cough, expectoration, wheezing) were compared before and after treatment. Results The FEV1%, FVC% and PEF% of the two groups were significantly improved at one month and three months of treatment(P<0.05), and the improvement of the treatment group was better than that of the control group at the same time(P<0.05). After three months of treatment, FeNO, percentage of eosinophils, in the two groups were lower than those in the group before treatment(P<0.05), and the scores in the treatment group were lower than those in the same period of the control group(P<0.05). After three months of treatment, the ACT score of the two groups were higher than those in the group before treatment(P<0.05), and the treatment group was higher than the control group(P<0.05). After three months of treatment,cough, expectoration, pant, chest distress and wheezing scores were decreased in the treatment group(P<0.05),there was no significant change of symptoms and signs in control group(P>0.05).Conclusion The combination of traditional Chinese medicine

关 键 词：哮喘 膏剂 埋线 中医疗法 

分 类 号：R562.25[医药卫生—呼吸系统] R244.9[医药卫生—内科学]