颊黏膜含化与阴道后穹窿置入米索前列醇在促进宫颈成熟中的应用效果对比  

Comparison of the application effect of misoprostol through buccal mucosa inclusion and posterior vaginal fornix insertion in promoting cervical ripening

作　　者：王彩英 黄长芳 雷菊玲 续靖宁 WANG Cai-ying;HUANG Chang-fang;LEI Ju-ling;XU Jing-ning(Obstetrics Department,Northwest Women's and Children's Hospital,Xi'an 710061,China)

机构地区：[1]西北妇女儿童医院产科

出　　处：《临床医学研究与实践》2019年第35期163-165,共3页Clinical Research and Practice

摘　　要：目的探究颊黏膜含化与阴道后穹窿置入米索前列醇在促进宫颈成熟中的应用效果。方法选取我院2016年10月至2018年10月收治的300例宫颈不成熟足月妊娠孕妇,按照不同给药方法将其分为A组和B组,各150例。A组予以颊黏膜含化米索前列醇,B组予以阴道后穹窿置入米索前列醇。对比两组Bishop评分、促进宫颈成熟效果、计划分娩成功率、米索前列醇给药情况、新生儿情况。结果给药后,两组患者的Bishop评分均升高,且B组高于A组(P<0.05)。B组患者促进宫颈成熟总有效率为84.00%,高于A组患者的65.33%(P<0.05)。B组计划分娩成功率为75.33%,高于A组的56.00%(P<0.05)。B组的米索前列醇用量、米索前列醇使用次数少于A组,给药至临产时间短于A组(P<0.05)。两组新生儿Apgar评分、出生体质量、窒息发生率比较,差异无统计学意义(P>0.05)。结论米索前列醇可促进宫颈成熟,与颊黏膜含化相比,阴道后穹窿置入米索前列醇用药少,药效发挥快,促宫颈成熟效果更佳,计划分娩成功率更高,且对新生儿质量无明显影响,故采用米索前列醇促进宫颈成熟时,应尽量选择阴道后穹窿置入米索前列醇。Objective To investigate the application effects of misoprostol through buccal mucosa inclusion and posterior vaginal fornix insertion in promoting cervical ripening.Methods From October 2016 to October 2018,300 pregnant women with cervical immature term pregnancy were selected and divided into group A and group B according to the different administration methods,with 150 cases in each group.The group A was given misoprostol through buccal mucosa inclusion,while the group B was given misoprostol through posterior vaginal fornix insertion.The Bishop scores,cervical ripening promotion effects,planned delivery success rates,misoprostol administration and newborn were compared between the two groups.Results After administration,the Bishop scores of both groups increased,and that of the group B was higher than the group A(P<0.05).The total effective rate of promoting cervical ripening in the group B was 84.00%,which was higher than 65.33%in the group A(P<0.05).The success rate of planned delivery in the group B was 75.33%,which was higher than 56.00%in the group A(P<0.05).The dosage and administration times of misoprostol in the group B were less than those in the group A,and the time from administration to labor was shorter than that in the group A(P<0.05).There were no significant differences in Apgar scores,birth weight and incidences of asphyxia between the two groups(P>0.05).Conclusion Misoprostol can promote cervical ripening.Compared with buccal mucosa inclusion,misoprostol placed in the posterior vaginal fornix has many advantages,such as less medication,faster efficacy,better effect of promoting cervical ripening,higher success rate of planned delivery and no significant impact on the quality of newborn.Therefore,when misoprostol is used to promote cervical ripening,it should be given through posterior vaginal fornix insertion as far as possible.

关 键 词：宫颈不成熟 足月妊娠孕妇 米索前列醇 颊黏膜含化 阴道后穹窿 

分 类 号：R719.3[医药卫生—妇产科学]