白癜风治疗研究热点追踪及前沿和演变路径可视化分析  

Visual Analysis of Research Hotspot and Frontier Evolution Paths of Vitiligo Treatment

作　　者：张亚妮[1] 吕伟[2] 张理涛[3] ZHANG Yani;LYU Wei;ZHANG Litao(Department of Library,The Second Affiliated Hospital of Xi′an Jiaotong University,Xi′an 710004,China;Department of Oncology,The Second Affiliated Hospital of Xi′an Jiaotong University,Xi′an 710004,China;The First Department of Dermatology,Affiliated Hospital of Tianjin Academy of Traditional Chinese Medicine,Tianjin 300120,China)

机构地区：[1]西安交通大学第二附属医院图书馆,西安710004 [2]西安交通大学第二附属医院肿瘤病院,西安710004 [3]天津市中医药研究院附属医院皮肤一科,天津300120

出　　处：《医学综述》2019年第22期4560-4567,4572,共9页Medical Recapitulate

基　　金：陕西省出版科学基金项目(14CSC09);西安交通大学第二附属医院科研基金项目(YJ(GL)201402)

摘　　要：目的通过绘制可视化科学知识图谱分析白癜风研究热点及前沿和演变路径,为后续相关研究提供参考依据。方法收集1966—2019年Web of Science核心合集数据库白癜风治疗相关文献,运用CiteSpace 5.5.R2和VOSviewer1.6.12.0信息可视化软件绘制白癜风各研究主题科学知识图谱,探索白癜风知识基础、合作力量特征、研究热点和前沿演变路径。结果共检索文献1014篇,美国、印度、意大利发文最多,白癜风和非黑素瘤皮肤癌、转移性黑素瘤、药物/生物学/皮肤移植等为研究热点,最前沿研究内容有转移性黑素瘤及单克隆抗体易普利姆玛(ipilimumab)用于治疗晚期黑素瘤等。结论基于Web of Science数据平台的科学知识图谱可视化研究,可以客观地展示白癜风治疗研究领域研究热点和演变路径,对于探索复杂大数据中潜在的科学知识具有重要意义,相关人员可借鉴其研究结果。Objective To analyze the research hotspots and frontier evolution paths of vitiligo by drawing the scientific knowledge maps,and provide reference for subsequent related research.Methods The literature on the treatment of vitiligo in the Web of Science core collection database from 1966 to 2019 was collected.CiteSpace 5.5.R2 and VOSviewer 1.6.12.0 information visualization software were used to draw the scientific knowledge maps of various research topics in vitiligo,and to explore the knowledge base,cooperation strength characteristics and research hotspots and frontier evolution paths of vitiligo.Results A total of 1014 articles were searched,mostly from the United States,India,and Italy.Vitiligo and non-melanoma skin cancer,metastatic melanoma,and drug/biology/skin transplantation were the research hotspots.The most cutting-edge research content was metastatic melanoma and monoclonal antibody(ipilimumab)used to treat advanced melanoma.Conclusion The scientific knowledge map based on Web of Science data platform can be used to objectively demonstrate the research hotspots and evolution paths of vitiligo treatment research,which is of great significance for exploring potential scientific knowledge in complex big data that relevant practitioners can learn from.

关 键 词：白癜风 表皮移植 皮肤转移 光疗 CiteSpace软件 VOSviewer软件 

分 类 号：R758.41[医药卫生—皮肤病学与性病学]