4387例性病门诊患者沙眼衣原体、淋球菌、解脲脲原体感染情况分析  

The Prevalences of Chlamydia Trachomatis,Neisseria Gonorrhoeae and Ureaplasma Urealyticum Infections in 4387 Outpatients from Sexually Transmitted Disease Clinic

作　　者：曲沛[1] 郭杰[1] 李韦杰 徐新民[1] 郭晶晶[1] 方茜 王雅杰 QU Pei;GUO Jie;LI Wei-jie;XU Xin-min;GUO Jing-jing;FANG Qian;WANG Ya-jie(Department of Clinical Laboratory,Beijing Ditan Hospital,Capital Medical University,Beijing,100015,China)

机构地区：[1]首都医科大学附属北京地坛医院

出　　处：《标记免疫分析与临床》2019年第12期1994-1996,2002,共4页Labeled Immunoassays and Clinical Medicine

基　　金：新发突发传染病研究北京市重点实验室开放课题(编号:DTKF201801)

摘　　要：目的了解性病门诊患者沙眼衣原体(CT)、淋球菌(NG)和解脲脲原体(UU)的感染情况,为临床的诊断及治疗提供实验室依据。方法回顾性分析4387例性病门诊患者CT、NG、UU检测结果。结果在4387份标本中,男性样本2639例、女性样本1748例。其中男性患者CT、NG、UU阳性率分别为9.6%(253/2639)、11.0%(290/2639)和12.5%(329/2639),女性患者CT、NG、UU阳性率分别为8.5%(149/1748)、2.3%(41/1748)和38.2%(668/1748),不同性别患者NG、UU阳性率之间差异均有统计学意义(P<0.01)。CT、NG、UU在小于20岁年龄段患者中阳性率均为最高,分别为23.1%、11.3%、35.4%,不同年龄段患者CT、NG、UU阳性率之间差异均有统计学意义(P<0.01)。在混合感染中,不同性别CT+UU和CT+NG阳性率之间差异均有统计学意义(P<0.01),男性患者CT+NG混合感染率最高,为47.4%;女性患者CT+UU混合感染率最高,为71.0%。结论随着性传播疾病感染的低龄化,应加强中青年人群性病防治工作,同时应对病原体的混合感染情况加以重视,以明确诊断和治疗。Objective To study the prevalences of Chlamydia trachomatis(CT),Neisseria gonorrhoeae(NG)and Urea plasma urealyticum(UU)in outpatients of STD,and provide laboratory basis for clinical diagnosis and treatment.Methods The CT,NG and UU results of 4387 outpatients with STD were retrospectively analyzed.Results A total of 4387 specimens were retrospectively analyzed,including 2639 male samples and 1748 female samples.The positive rates of CT,NG and UU in male patients were 9.6%(253/2639),11.0%(290/2639)and 12.5%(329/2639),respectively,while the positive rates of CT,NG and UU in female patients were 8.5%(149/1748),2.3%(41/1748)and 38.2%(668/1748),respectively.There were statistically significant differences in the positive detection rates of NG and UU between different genders(P<0.01).Positive rates of CT,NG,and UU were the highest in the age group of below 20 years old,namely 23.1%(30/130),11.3%(13/115),and 35.4%(46/130),respectively.There were statistically significant differences in the positive detection rates of CT,NG and UU between different age groups(P<0.01).In mixed infection,the positive rates of CT+UU and CT+NG in different genders were significantly different(P<0.01).The mixed infection rate of CT+NG in male patients was the highest(47.4%).The mixed infection rate of CT+UU in female patients was the highest(71.0%).Conclusion The positive rate of STDs in young people is on the rise.The prevention and treatment of STD in young and middle-aged people should be strengthened.Meanwhile,the mixed infection of pathogens should be paid attention to,so as to make accurate diagnosis and treatment.

关 键 词：性病 沙眼衣原体 淋球菌 解脲脲原体:混合感染 

分 类 号：R75[医药卫生—皮肤病学与性病学]