布托啡诺复合舒芬太尼对老年关节置换术患者自控镇痛的临床效果探究  

Study on the clinical effect of butorphanol combined with sufentanil on patient-controlled analgesia in elderly patients undergoing arthroplasty

作　　者：陈燕中 邬文伟[1] 刘宇权 廖亿粦[1] CHEN Yanzhong;WU Wenwei;LIU Yuquan;LIAO Yilin(Department of Anesthesiology,Meizhou People's Hospital,Guangdong,Meizhou 514031,China)

机构地区：[1]广东省梅州市人民医院麻醉科

出　　处：《中国医药科学》2019年第23期218-220,共3页China Medicine And Pharmacy

摘　　要：目的分析布托啡诺复合舒芬太尼对老年关节置换术患者自控镇痛的临床效果与安全性。方法以2017年1月~2018年9月,我院收治择期老年关节置换术患者60例入组,根据随机把患者分为对照组及观察组,每组各30例,分别采用舒芬太尼静脉自控镇痛以及布托啡诺复合小剂量舒芬太尼静脉自控镇痛,对比疼痛水平以及不良事件发生情况。结果观察组术后第4h、8h、12h VAS疼痛水平与对照组比较,差异无统计学意义(P> 0.05),观察组术后24h疼痛VAS水平低于对照组,差异有统计学意义(P <0.05)。在恶心呕吐、不良事件合计发生率对比中,观察组低于对照组,差异有统计学意义(P <0.05)。结论布托啡诺复合舒芬太尼用于老年关节置换术患者自控镇痛,可以降低不良事件发生风险,减少恶心呕吐。Objective To analyze the clinical effect and safety of butorphanol combined with sufentanil on patientcontrolled analgesia in elderly patients undergoing arthroplasty. Methods 60 patients who underwent elective arthroplasty in our hospital from January 2017 to September 2018 were enrolled in this study.The patients were divided into control group and observation group according to the randomization method,30 cases in each group.The control group was given sufentanil intravenous patient-controlled analgesia,while the observation group was given butorphanol combined with low-dose sufentanil for intravenous patient-controlled analgesia.The level of pain and the incidence of adverse events were compared. Results There were no significant differences in VAS pain levels at 4 h,8 h,and 12 h after operation between the observation group and the control group(P > 0.05).The VAS pain level at 24 h after operation in the observation group was lower than that in the control group,and the difference was statistically significant(P < 0.05).The incidence of adverse events of nausea and vomiting in the observation group was lower than that in the control group,and the difference was statistically significant(P < 0.05). Conclusion Butorphanol combined with sufentanil for patient-controlled analgesia in elderly patients undergoing arthroplasty can decrease the risk of adverse events and reduce the incidence of nausea and vomiting.

关 键 词：关节置换术 自控镇痛 舒芬太尼 布托啡诺 

分 类 号：R658.3[医药卫生—外科学]