药学干预对医院抗生素不合理应用的影响  

The Influence of Pharmaceutical Intervention on the Unreasonable Use of Antibiotics in Our Hospital

作　　者：刘红[1] LIU Hong(Surgical Pharmacy,Xuzhou Central Hospital,Xuzhou Jiangsu 221009,China)

机构地区：[1]徐州市中心医院外科药房

出　　处：《中国继续医学教育》2019年第36期130-133,共4页China Continuing Medical Education

摘　　要：目的探讨药学干预对我院抗生素不合理应用的影响。方法选择采用抗生素治疗的患者300例随机分为甲组(n=150)与乙组(n=150),乙组患者仅采用常规用药指导,甲组患者采用药学干预,比较两组患者的抗生素使用情况。结果甲组患者的抗生素使用种类、用药频度、利用指数显著少于乙组,使用时间、费用显著多于乙组(P <0.05)。甲组患者的抗生素不合理用药发生率、不良反应发生率显著低于乙组,用药依从性、用药满意度显著高于乙组(P <0.05)。结论药学干预有利于促进临床合理使用抗生素,减少抗生素使用种类,降低其用药频度,减少治疗费用,患者的用药依从性高,不良反应发生率低,用药满意度高,干预效果良好。Objective To explore the influence of pharmaceutical intervention on the irrational use of antibiotics in our hospital. Methods 300 patients who were treated with antibiotics were randomly divided into group A(n=150) and group B(n=150). Group B only used conventional medication guidance, and group A patients used pharmaceutical intervention to compare the antibiotic use of the two groups. Results The type, frequency and index of antibiotic use in group A were significantly lower than those in group B, and the time and cost of antibiotic use were significantly higher than those in group B(P < 0.05). The incidence of irrational use of antibiotics and adverse reactions in group A was significantly lower than that in group B, and the compliance and satisfaction with antibiotics were significantly higher than those in group B(P < 0.05). Conclusion Pharmaceutical intervention can promote the rational use of antibiotics, reduce the types of antibiotics, reduce the frequency of drug use, reduce the cost of treatment. Patients with high compliance, low incidence of adverse reactions, high satisfaction with drug use, and good effect of intervention.

关 键 词：抗生素 药剂师 药学干预 不合理应用 不良反应 用药满意度 

分 类 号：R978[医药卫生—药品]