蚜虫报警信息素(E)-β-farnesene及其类似物的生物活性和作用机制研究进展  

Research progress on bioactivities and mechanism of aphid alarm pheromone(E)-β-farnesene and its analogues

作　　者：秦耀果 杨朝凯 凌云[1] 陈巨莲[2] 段红霞[1] 杨新玲[1] QIN Yaoguo;YANG Zhaokai;LING Yun;CHEN Julian;DUAN Hongxia;YANG Xinling(Department of Applied Chemistry,College of Science,China Agricultural University,Beijing 100193,China;State Key Laboratory of Plant Pest Biology,Institute of Plant Protection,Chinese Academy of Agricultural Sciences,Beijing 100193,China)

机构地区：[1]中国农业大学理学院应用化学系,北京100193 [2]中国农业科学院植物保护研究所,植物病虫害生物学国家重点实验室,北京100193

出　　处：《农药学学报》2019年第5期643-659,共17页Chinese Journal of Pesticide Science

基　　金：国家重点研发计划(2017YFD0200504,2017YFD0201701);国家自然科学基金(31371946,31871966,31772207,31071717);中国博士后科学基金项目(2018M631646)

摘　　要：蚜虫报警信息素[(E)-β-farnesene,简称EBF]是蚜虫腹管分泌的一种物质,它能对同种其他个体产生报警反应,使其迅速逃离危险现场。作为天然蚜虫信息素,EBF通过蚜虫嗅觉系统的气味结合蛋白OBPs和嗅觉受体ORs发挥作用,具有驱避、杀蚜、增效等多种生物活性,可用于蚜虫的行为调控,但由于其结构中存在的共轭双键而导致其稳定性差,从而限制了其实际应用。本文在简介蚜虫报警信息素EBF的基础上,系统介绍了EBF的结构修饰和改造进展,并对EBF及其类似物的生物活性和作用机制进行了综述,最后对EBF及其类似物的应用前景进行了展望,期望为开发具有实用价值的生态友好型蚜虫控制剂提供参考。The aphid alarm pheromone,(E)-β-farnesene(EBF),is a natural product secreted from the aphid cornicle to warn other companions of danger.As a natural aphid pheromone,(E)-β-farnesene can interact with odorant binding proteins(OBPs)and olfactory receptor(ORs)in the aphid olfactory system.Because of its multiple biological activities such as repellent,aphicidal and synergistic effects,(E)-β-farnesene is regarded as an aphid behavior control agent.However,its application was a challenge due to its instability arising from the conjugated double bonds in EBF.A brief introduction of the current situation in aphid control was covered in this review.The discovery and activity of(E)-β-farnesene was also summaried.According to the recent results obtained in the studies of EBF analogues,the structure modification and optimization of(E)-β-farnesene,the activities of EBF analogues and their mode of action were reviewed.And the outlook on the trend of EBF analogues as candidates of eco-friendly aphicide is proposed.

关 键 词：蚜虫报警信息素 (E)-β-farnesene类似物 生物活性 作用机制 生态友好型蚜虫控制剂 

分 类 号：S482.3[农业科学—农药学]