SF-36和EQ-5D量表在慢性肾脏病患者生命质量评估中的对比研究  

Comparative study of SF- 36 and EQ- 5D in evaluating quality of life for patients with chronic kidney disease

作　　者：彭颢 陈露 卓琳[3] 马艺菲 刘水 汪秀英[4] 卓朗 PENG Hao;CHEN Lu;ZHUO Lin;MA Yifei;LIU Shui;WANG Xiuying;ZHUO Lang(Department of Clinical Medicine,Xuzhou Medical University,Xuzhou 221004,China;School of Public Health,Xuzhou Medical University,Xuzhou 221004,China;School of Basic Medical Sciences,Xinxiang Medical University,Xinxiang 453003,China;Department of Nephrology,Xuzhou Central Hospital,Xuzhou 221009,China)

机构地区：[1]徐州医科大学临床医学系,江苏徐州221004 [2]徐州医科大学公共卫生学院,江苏徐州221004 [3]新乡医学院基础医学院,河南新乡453003 [4]徐州市中心医院肾脏内科,江苏徐州221009

出　　处：《东南大学学报（医学版）》2019年第6期1024-1028,共5页Journal of Southeast University(Medical Science Edition)

基　　金：江苏省大学生创新计划基金资助项目(201710313064X);江苏省高校优秀教师和校长境外研修计划基金资助项目(20180120)

摘　　要：目的:比较健康状况调查简表(SF-36)和五维度欧洲生命质量量表(EQ-5D)对慢性肾脏病患者生命质量的评价效果。方法:采用SF-36和EQ-5D量表对徐州市中心医院112例慢性肾脏病患者入院和出院时的生命质量进行评估,比较EQ-5D的视觉标尺评分(EQ-VAS)和SF-36总分、生理总测量(PCS)和心理总测量(MCS)评分的均值、z标准分。结果:112例患者EQ-VAS评分出院时(0.72±0.20)高于入院时(0.58±0.20)(P<0.05),出院时患者SF-36总分、PCS评分和MCS评分依次为(60.75±23.16)、(59.84±23.59)和(61.65±25.17)分,高于入院时的(41.86±21.65)、(42.26±20.98)和(41.46±24.13)分(P<0.05)。EQ-VAS出入院z标准分的差值(0.8278)高于SF-36 z标准分的差值(0.7781)(P<0.05)。EQ-VAS评分与SF-36总分、PCS、MCS总评分的Pearson相关系数分别为0.555、0.534、0.532(P<0.01)。对应分析显示EQ-VAS的区分度优于SF-36总分。结论:EQ-5D和SF-36量表均能评价慢性肾脏病患者的生命质量,EQ-VAS评分的反应度、区分度高于SF-36,EQ-VAS更简单方便,是慢性肾脏病患者生命质量评价的有效工具。Objective:To compare the effect of Short Form 36(SF-36)and Five-Dimensional Euro Quality of Life(EQ-5D)on the quality of life for patients with chronic kidney disease.Methods:One hundred and twelve patients with chronic kidney disease in Xuzhou Central Hospital were assessed by SF-36 and EQ-5D scales at admission and discharge.EQ-5D visual scale(EQ-VAS)and SF-36,physical component summary(PCS)and mental component summary(MCS)scores,as well as the standardized z scores were compared.Results:The mean of EQ-VAS score of the 112 patients at discharge(0.72+0.20)was higher than that of admission(0.58+0.20)(P<0.05).The total score of SF-36,PCS and MCS of discharged patients were 60.75+23.16,59.84+23.59 and 61.65+25.17,respectively,which were higher than those of admission(41.86+21.65,42.26+20.98 and 41.46+24.13)(P<0.05).The z standardized score difference of EQ-VAS(0.8278)was higher than that of SF-36(0.7781)(P<0.05).The correlation coefficients between EQ-VAS score and SF-36 score,PCS score and MCS score were 0.555,0.534 and 0.532,respectively(P<0.01).Correspondence analysis showed that the EQ-VAS score was better than the SF-36 total score.Conclusion:Both EQ-5D and SF-36 scales can evaluate the quality of life for patients with chronic kidney disease.EQ-VAS score is more appropriate than SF-36 due to its high capacity of reactivity and discrimination.EQ-VAS is an effective tool for evaluating the quality of life for patients with chronic kidney disease.

关 键 词：健康状况调查简表 五维度欧洲生命质量量表 视觉标尺 慢性肾脏病 生命质量 

分 类 号：R195.1[医药卫生—卫生统计学]