子痫前期合并低蛋白血症对产妇妊娠结局的影响  

Effect of preeclampsia complicated with hypoalbuminemia on pregnancy outcome of parturients

作　　者：吴晓爽[1] 苗丽竺 WU Xiao-shuang;MIAO Li-zhu(Department of the Fifth Ward Obstetrics,Dalian Maternal and Child Health Hospital and Dalian Maternal and Obstetric Hospital,Liaoning Province,Dalian 116600,China;Operating Room,Dalian Maternal and Child Health Hospital and Dalian Maternal and Obstetric Hospital,Liaoning Province,Dalian 116600,China)

机构地区：[1]大连市妇幼保健院暨大连市妇产医院产五病房,辽宁大连116600 [2]大连市妇幼保健院暨大连市妇产医院手术室,辽宁大连116600

出　　处：《中国当代医药》2019年第35期153-155,共3页China Modern Medicine

摘　　要：目的探讨子痫前期合并低蛋白血症对产妇妊娠结局的影响。方法选取2017年7月~2018年7月我院产科收治的104例子痫前期患者作为研究对象,根据患者的血清清蛋白检测结果,将其分为低蛋白血症组(n=57)和非低蛋白血症组(n=47)。比较两组患者的血压水平、发病时间、终止妊娠时间等临床资料,记录并统计两组患者的并发症情况以及围生结局情况。结果低蛋白血症组患者的血压水平高于非低蛋白血症组,发病时间和终止妊娠时间均早于非低蛋白血症组,差异有统计学意义(P<0.05);低蛋白血症组患者的并发症总发生率为57.89%,高于非低蛋白血症组的25.53%,差异有统计学意义(P<0.05);低蛋白血症组的胎儿生长受限、胎儿窘迫、新生儿窒息及围生儿死亡的发生率均高于非低蛋白血症组,新生儿体重低于非低蛋白血症组,差异有统计学意义(P<0.05)。结论子痫前期合并低蛋白血症对产妇妊娠结局有着显著的不利影响,患者的并发症较多,围生结局较差,因此临床要适时补充清蛋白,密切监测病情变化,必要时及时终止妊娠。Objective To investigate the effect of preeclampsia complicated with hypoalbuminemia on pregnancy outcome of parturients. Methods From July 2017 to July 2018, 104 patients with preeclampsia treated in obstetrics department of our hospital were selected as the subjects. According to the results of serum albumin test, the patients were divided into hypoalbuminemia group(n=57) and non-hypoalbuminemia group(n=47). The clinical data of blood pressure level, onset time and termination time of pregnancy between the two groups were compared, and the complications and perioperative outcomes of the two groups were recorded and counted. Results The blood pressure level in the hypoalbuminemia group was higher than that in the non-hypoalbuminemia group, and the onset time and termination time of pregnancy were earlier than those in the non-hypoalbuminemia group, the differences were statistically significant(P<0.05). The total incidence of complications in hypoalbuminemia group was 57.89%, which was higher than that in non-hypoalbuminemia group(25.53%), and the difference was statistically significant(P<0.05). The incidence of fetal growth restriction, fetal distress, neonatal asphyxia and perinatal death of the hypoproteinemia group were higher than that of the non-hypoproteinemia group, and the weight of the newborn was lower than that of the non-hypoproteinemia group, the differences were statistically significant(P<0.05). Conclusion Patients with preeclampsia combined with hypoproteinemia have a significant adverse effect on maternal pregnancy outcome. There are more complications, and the perinatal outcome is worse. Therefore, albumin should be supplemented in the clinic, and the changes of the disease should be monitored closely, and pregnancy should be terminated in time if necessary.

关 键 词：子痫前期 低蛋白血症 并发症 妊娠结局 

分 类 号：R714.244[医药卫生—妇产科学]