止嗽散联合脱敏煎对感染后咳嗽患者临床效果的影响及安全性分析  

Effect and safety of Zhisou Powder combined with Tuomin Decoction on patients with postinfectious cough

作　　者：刘燕 马洁 王蓓蓓 王韶华 LIU Yan;MA Jie;WANG Bei-bei;WANG Shao-hua(Department of Respiratory Medicine,Beijing Hospital of Integrated Traditional Chinese and Western Medicine,Beijing 100039)

机构地区：[1]北京市中西医结合医院呼吸科

出　　处：《世界中西医结合杂志》2019年第12期1735-1737,共3页World Journal of Integrated Traditional and Western Medicine

基　　金：国家自然科学基金青年基金项目(81503448)

摘　　要：目的观察止嗽散联合脱敏煎加减治疗感染后咳嗽的临床疗效及安全性。方法72例感染后咳嗽患者随机分为治疗组和对照组,每组36例,治疗组服用止嗽散联合脱敏煎加减治疗,对照组采用复方愈酚喷托纳敏治疗,疗程为10 d,观察两组治疗后临床疗效及不良反应发生情况。结果治疗组临床愈显率明显高于对照组(P<0.05),差异具有统计学意义。与对照组比较,治疗组治疗后VAS评分明显降低,咳嗽缓解时间明显减少,不良反应发生率明显降低(P<0.05),差异具有统计学意义。结论止嗽散合脱敏煎加减治疗感染后咳嗽可有效缓解临床症状,降低不良反应发生率,提高临床治疗效果。Objective To observe effect and safety of modified Zhisou Powder with Tuomin Decoction in the treatment of postinfectious cough.Methods 72 patients with postinfectious cough were randomly divided into the treatment group and the control group,with 36 cases in each group.The treatment group was treated with modified Zhisou Powder and Tuomin Decoction(granules),while the control group was treated with Compound Guaifenesine Pentoxyverine Citrate and Chlorphenamine Maleate for 10 days.The curative effect and adverse reactions in both groups were observed after treatment.Results The effective rate in the treatment group was significantly higher than that in the control group(P<0.05)with statistical significance.Compared with the control group,the treatment group had significance reductions in VAS score,cough remission time,and the rate of adverse reactions(P<0.05),with statistical significance.Conclusion Modified Zhisou Powder with Tuomin Decoction can alleviate symptoms,reduce adverse reactions and improve clinical effect on postinfectious cough.

关 键 词：止嗽散 脱敏煎 感染后咳嗽 安全性分析 

分 类 号：R256.11[医药卫生—中医内科学]