基于碳纳米管原生手性的手性电化学传感器的研究及应用进展  

A Review:Recent Progress and Application of Chiral Electrochemical Sensors Based on the Inherent Chirality of Carbon Nanotubes

作　　者：杨洋 朱志伟[1] YANG Yang;ZHU Zhi-wei(College of Chemistry and Molecular Engineering,Peking University,Beijing 100871)

机构地区：[1]北京大学化学与分子工程学院

出　　处：《分析科学学报》2019年第6期732-740,共9页Journal of Analytical Science

基　　金：国家自然科学基金(No.21775007)

摘　　要：对手性物质进行识别研究在化学生物学及药学等领域具有重要的意义。手性传感器因其制备简单、检测快速、价格低廉,以及可实时、在线分析等优点,成为了手性识别检测领域的一个重要发展方向,其中尤以手性电化学传感器在手性选择剂的筛选方面的独特价值而特别受到人们的关注。碳纳米管(CNTs)可看作是由石墨片卷成的圆柱体,依据Hamada命名规则,其不同的结构形态由参数(n,m)来确定,n≠m≠0时的单壁碳纳米管可表现出手性,而某些情况下得到的多壁碳纳米管也可能具有手性。本文首先对目前主要的手性识别机理和CNTs的手性性质进行了详细介绍,随后对基于CNTs原生手性的手性电化学传感器的研究现状、优势及其存在的问题进行了综述,并展望了其未来的发展方向。The study of chiral recognition of enantiomers is playing an increasingly important role in chemical biology and pharmacology significance.The chiral sensor has attracted many researchers’ attention due to its advantages of simple preparation,rapid detection,low cost,real-time and online analysis and so on,in particular to electrochemical chiral sensors with unique value in the selection of chiral selectors.According to the Hamada nomenclature,n and m are two integers that decide the characteristics of a tube.The chiral single walled carbon nanotubes(SWCNTs) can be prepared by rolling up a graphite sheet into a seamless tube under the condition of the roll-up index being n≠m≠0,and its chiroptical activity owing to kink sites has been observed.In some cases,multi-walled carbon nanotubes also show chirality.In this review,the main mechanism of chiral recognition and the chiral properties of carbon nanotubes are introduced in detail.The research progress,advantages and current problems of chiral electrochemical sensors based on the inherently chiral properties of carbon nanotubes were reviewed,and a prospect of the future development of this kind of chiral electrochemical sensors was made.

关 键 词：手性电化学传感器 碳纳米管 原生手性 

分 类 号：O657.1[理学—分析化学]