RuSiNPs/SnO2复合膜修饰电极用于沙丁胺醇的检测  

Research on Detection of Salbutamol Using RuSiNPs/SnO2 Complex Modified GCE

作　　者：单学凌[1] 杨天宇 殷嘉豪 潘瑜婷 陈智栋[1] SHAN Xueling;YANG Tianyu;YIN Jiahao;PAN Yuting;CHEN Zhidong(School of Petrochemical Engineering,Changzhou University,Changzhou 213164,China;School ofInternational Education and Exchange,Changzhou University,Changzhou 213164,China)

机构地区：[1]常州大学石油化工学院,江苏常州213164 [2]常州大学国际教育交流学院,江苏常州213164

出　　处：《常州大学学报（自然科学版）》2020年第1期22-30,共9页Journal of Changzhou University：Natural Science Edition

基　　金：江苏省高校自然科学研究资助项目(18KJB150001)

摘　　要：采用一步法制得三联吡啶钌(Ru(bpy)32+)复合的二氧化硅(SiO2)纳米粒子(RuSiNPs),并将其与氧化锡(SnO2)共同修饰在玻碳电极(GCE)表面,构建了一种高灵敏度的增敏型电化学发光(ECL)传感器,并将其应用于沙丁胺醇测定的研究。当一定量的沙丁胺醇加入到电解液之中后,ECL强度得到加强,且当沙丁胺醇浓度在10~5.0×104 nmol·L-1范围内时,增加的ECL强度与沙丁胺醇浓度的对数呈现很好的线性关系,检测限为3.2 nmol·L-1(S/N=3)。此方法在应用到实际样品中沙丁胺醇含量的测定时,具有很好的抗干扰能力,增加了电化学发光法在现实领域的应用潜力。The Ru(bpy)32+immobilized SiO2 nanoparticles(RuSiNPs)were successfully prepared through a one-step reaction.After that,the RuSiNPs and SnO2 were co-modified on GCE surface to construct a highly sensitive electrochemiluminescence(ECL)sensor for salbutamol.When a certain amount of salbutamol was present in the electrolyte,the ECL intensity was enhanced and showed a good correlation to salbutamol concentration in the range 10-5.0×104 nmol·L-1,with a detection limit of 3.2 nmol·L-1(S/N=3).Furthermore,the proposed ECL sensor exhibited an excellent anti-interference ability when it was applied for salbutamol detection in real samples.It significantly increased the application potential of ECL method in real-world.

关 键 词：电化学发光 钌硅纳米粒子 氧化锡 沙丁胺醇 高灵敏度 

分 类 号：O657.12[理学—分析化学]