18F-FDG PET/CT对肺磨玻璃结节的诊断价值  

Diagnostic Value of 18F-FDG PET/CT for Lung Ground Glass Nodules

作　　者：田金玲[1] 王朋[1] 陈海波 胡伟[1] 秦灏[1] 代文莉[1] Tian Jinling;Wang Peng;Chen Haibo;Hu Wei;Qin Hao;Dai Wenli(Department of Nuclear Medicine,Yichang Central People's Hospital,The First College of Clinical Medical Science,China Three Gorges University&Yichang Key Laboratory of Nuclear Medicine and Molecular Image,Yichang 443003,China)

机构地区：[1]三峡大学第一临床医学院(宜昌市中心人民医院)核医学科&宜昌市核医学分子影像重点实验室

出　　处：《巴楚医学》2019年第4期44-47,共4页Bachu Medical Journal

基　　金：湖北省自然科学基金项目（No:2018CFB147）;宜昌市医疗卫生科研指导性项目（No:K17-05）

摘　　要：目的:探讨^18F-FDG PET/CT对肺部磨玻璃结节(GGNs)的诊断价值。方法:回顾性分析我院PET中心2013年9月~2018年9月诊断为肺GGNs并有手术病理结果的患者134例,分析SUVmax在良恶性GGNs中的诊断价值。结果:良性GGNs 10例(7.46%),恶性GGNs 124例(92.54%),两组之间SUVmax比较,差异有统计学意义(P<0.05)。SUVmax诊断良恶性肺GGNs的受试者工作特征曲线(ROC)下面积为0.805,获得的最佳界点为0.53,诊断效能中等,以此为临界值,^18F-FDG PET/CT诊断肺GGNs的灵敏度为89.5%,特异度为60.0%。结论:^18F-FDG PET/CT对于肺GGNs的诊断有一定的帮助,但特异性不太高,在临床实践中,对于肺GGNs的诊疗要循序渐进。Objective:To investigate the diagnostic value of ^18F-FDG PET/CT for lung ground glass nodules(GGNs).Methods:A total of 134 lung GGNs cases with surgical pathology results from September 2013 to September 2018 in the PET center were retrospectively analyzed.And the diagnostic value of SUVmax in benign and malignant GGNs were evaluated.Results:There were 10 cases of benign GGNs(7.46%)and 124 cases of malignant GGNs(92.54%),with a significant difference of SUVmax between two groups(P<0.05).The areas under receiver operating characteristic curve(ROC)of SUVmax in diagnosis of benign and malignant lung GGNs was 0.805,and the optimal threshold was 0.53,with moderate diagnostic efficacy.Taking 0.53 as SUVmax critical value,the sensitivity and specificity of ^18F-FDG PET/CT in diagnosis of lung GGNs were 89.5%and 60.0%,respectively.Conclusion:^18F-FDG PET/CT palys a helpful role in diagnosis of lung GGNs,but its specificity is not very high.In clinical practice,the diagnosis and treatment of lung GGNs should be carried out step by step.

关 键 词：肺磨玻璃结节 PET/CT ^18F-FDG 诊断效能 

分 类 号：R445.9[医药卫生—影像医学与核医学]