长双歧杆菌BB68S对便秘人群的通便和调节肠道菌群作用  

Effect of Bifidobacterium longum BB68S on Defaecation and Intestinal Flora in Constipation People

作　　者：李桂花 葛绍阳 桑跃 刘治麟 王然 LI Gui-hua;GE Shao-yang;SANG Yue;LIU Zhi-lin;WANG Ran(Beijing Advanced Innovation Center for Food Nutrition and Human Health,China Agricultural University,Beijing 100083;Hebei Technology Advanced Innovation Center for livestock food,Langfang 065201;Beijing Heyiyuan Biotechnology Company Limitid,Beijing 100089)

机构地区：[1]北京食品营养与人类健康高精尖创新中心中国农业大学 [2]河北省畜产食品技术创新中心 [3]北京和益源生物技术有限公司

出　　处：《中国奶牛》2019年第12期22-25,共4页China Dairy Cattle

摘　　要：功能性便秘是影响人类健康最普遍的疾病,通过调节饮食结构加以缓解是治疗便秘的主要方法。本研究的目的是评价长双歧杆菌BB68S的润肠通便作用和对便秘人群肠道菌群的影响。通过招募便秘人群试食BB68S样品(添加有BB68S的牛奶,活菌浓度约为10^10CFU/50mL)4周后发现,试食后与试食前相比,排便次数显著增加;最后一次排便状况积分及粪便性状积分显著降低;粪便中乙酸、丙酸、丁酸、总酸含量显著上升;益生菌双歧杆菌和乳酸杆菌的数量显著增加(P<0.05),潜在致病菌肠杆菌、肠球菌和产气荚膜梭菌的数量显著下降(P<0.05)。结果表明,BB68S样品具有良好的润肠通便功能,并能调节肠道菌群。本试验为开发含有BB68S相关功能食品提供了理论依据。Functional constipation is the most common disease affecting human health.Regulating dietary structure is the main method for treating constipation.The purpose of this study was to evaluate the effect of defaecation and intestinal flora of Bifidobacterium longum BB68 S.The experiment recruited constipation people.After taking the product containing 10^10 CFU/50 mL of BB68 S,compared to before,the number of bowel movements increased significantly,and the last defecation condition score decreased significantly;and the last fecal trait score decreased significantly;in additon,the contents of acetic acid,propionic acid,butyric acid and total acid in feces all increased significantly(P<0.05);the number of probiotic Bifidobacterium and Lactobacillus increased significantly(P<0.05),and the number of potential pathogn Enterobacterium,Enterococcus and Clostridium perfringens decreased significantly(P<0.05).The results showed that Bifidobacterium longum BB68 S had a good laxative function and regulated the intestinal flora.This study provides a theoretical basis for the development of functional beverages and other related products.

关 键 词：长双歧杆菌BB68S 通便 肠道菌群 

分 类 号：S8-1[农业科学—畜牧兽医]