不同时机丙种球蛋白治疗新生儿ABO溶血症的疗效  

Observation on the Effectiveness of Different Gamma Globulin in the Treatment of Neonatal ABO Hemolysis

作　　者：黄杰[1] 乾艾娜 甘斌[1] 何源[1] 魏贤[1] HUANG Jie;GAN Aina;GAN Bin;HE Yuan;WEI Xian(Department of Neonatology,Xiaogan Central Hospital,Xiaogan Hubei 432000,China)

机构地区：[1]湖北省孝感市中心医院新生儿科

出　　处：《中国继续医学教育》2020年第1期131-132,共2页China Continuing Medical Education

摘　　要：目的分析不同时机应用丙种球蛋白治疗新生儿ABO溶血症的有效性。方法在2018年1月—2018年12月进行研究,期间总共选取在我院接受诊治的80例ABO溶血症新生儿作为案例进行研究分析。以随机数字法的方式所选患儿划分为试验组与常规组。常规组与试验组分别采取晚期治疗与早期治疗方案。总结并对比两组患儿血清胆红素、Hb、RBC水平。结果治疗前两组患儿的血清胆红素、Hb以及RBC指标数据差异不突出,组间差异无统计学意义(P>0.05);治疗后试验组患儿的各项指标均显著优于常规组患儿,组间对比差异有统计学意义(P<0.05)。结论不同时机应用丙种球蛋白治疗新生儿ABO溶血症差异突出,出生后24 h内的早期治疗方案可以更好的保障整体治疗效果。Objective To analyze the effectiveness of different doses of gamma globulin in the treatment of neonatal ABO hemolysis.Methods A study was conducted between January 2018 and December 2018.A total of 80 ABO hemolytic neonates who were treated in our hospital were selected as a case study.The children selected by random number method were divided into experimental group and regular group.The advanced group and the experimental group were treated with advanced treatment and early treatment.The serum bilirubin,Hb and RBC levels in the two groups were summarized and compared.Results The differences in serum bilirubin,Hb and RBC data between the two groups were not significant.The comparison between the two groups was not significant(P>0.05).After treatment,the indexes of the experimental group were significantly better than the conventional ones.The data of the group were significantly different,and the comparison between the groups was significant(P<0.05).Conclusion The different time to apply gamma globulin in the treatment of neonatal ABO hemolytic disease is prominent,early treatment within 24 hours after birth can better guarantee the overall treatment effect.

关 键 词：新生儿学 不同时机 丙种球蛋白 新生儿 ABO溶血症 有效性 

分 类 号：R722[医药卫生—儿科]