炭疽芽孢杆菌基因组及基因分型研究进展  

Advances in the study of the genome and genotyping of Bacillus anthracis

作　　者：彭海燕 王鹏[2] 杨向东[2] PENG Hai-yan;WANG Peng;YANG Xiang-dong(School of Public Health,Dali University,Dali,Yunnan,China 671000;Yunnan Institute of Endemic Disease Control and Prevention,Yunnan Provincial Key Laboratory for Natural Epidemic Disease Prevention and Control Technology,Dali,Yunnan,China 671000)

机构地区：[1]大理大学公共卫生学院,云南大理671000 [2]云南省地方病防治所,云南省自然疫源性疾病防控技术重点实验室

出　　处：《中国病原生物学杂志》2019年第11期1361-1364,F0003,共5页Journal of Pathogen Biology

摘　　要：随着不同来源越来越多炭疽杆菌基因组测序的完成,为从全基因组水平研究炭疽杆菌提供了机遇。本文对炭疽杆菌基因组及其基因分型常用的两种方法MLVA和SNP的应用进行了概述,以了解炭疽杆菌的遗传特征及基因型别,为炭疽的防治工作提供科学依据。The completed genome sequencing of an increasing number of Bacillus anthracis from different sources offers researchers the chance to conduct related genomic studies.This review summarizes the use of MLVAs and SNPs,which are two methods commonly used to study the genome and genotype B.anthracis.These approaches will help to understand the genetic characteristics and genotypes of B.anthracis and provide a scientific basis for the prevention and control of anthrax.

关 键 词：炭疽杆菌 基因组 基因分型 MLVA SNP 综述 

分 类 号：R378.72[医药卫生—病原生物学]