比索洛尔联合福辛普利治疗扩张型心肌病合并室性心律失常的临床经济学评价  

Cost and Clinical Economic Evaluation of Bisoprolol Combined with Fosinopril in the Treatment of Dilated Cardiomyopathy with Ventricular Arrhythmia

作　　者：黄文平[1] 唐瑞璠[1] 许有凡[1] 张相杰[1] 李玉斌 HUANG Wenping;TANG Ruifan;XU Youfan;ZHANG Xiangjie;LI Yubin(Houjie Hospital of Dongguan,Dongguan 523945,China)

机构地区：[1]东莞市厚街医院

出　　处：《现代医院》2019年第12期1777-1780,共4页Modern Hospitals

摘　　要：目的进行扩张型心肌病合并室性心律失常的临床经济学评价。方法对某公立三级医院2015年1月—2018年12月收治的109例扩张型心肌病合并室性心律失常住院患者(低剂量比索洛尔联合福辛普利组治疗54例,高剂量比索洛尔联合福辛普利组治疗55例)的病例资料及费用明细数据进行回顾性分析和最小成本法分析。结果低剂量与高剂量比索洛尔联合福辛普利治疗扩张型心肌病合并室性心律失常患者平均住院天数为9.57天和6.85天;平均住院次数为2.13次与1.40次;平均住院总费用分别为11417.76元和6432.28元,均有显著性差异。分析表明,效果为有效的患者,高剂量组的平均住院总费用(2354.24元)明显低于低剂量组的平均住院总费用(7006.44元),两者有统计学差异。而效果为无效的患者,低剂量组与高剂量组治疗间住院医疗费用无显著性差异。结论扩张型心肌病合并室性心律失常综合治疗费用较高,实施高剂量比索洛尔联合福辛普利治疗后,住院天数、住院次数和平均住院总费用均降低;相同临床治疗效果下,高剂量比索洛尔联合福辛普利治疗有效率优于低剂量比索洛尔联合福辛普利治疗。可见,高剂量比索洛尔联合福辛普利治疗在临床经济学上更可行,且具有较好的推广应用价值。Objective Clinical economic evaluation of dilated cardiomyopathy with ventricular arrhythmia.Methods 109 patients with dilated cardiomyopathy complicated with ventricular arrhythmia admitted to A public tertiary hospital from January 2015 to December 2018(low dose bisoprolol combined with fosinopril group in 54 patients,high dose bisoprol Case data and cost breakdown data from 55 patients treated with Fosinopril were retrospectively analyzed and analyzed by least cost method.Results Low-dose and high-dose bisoprolol combined with fosinopril in patients with dilated cardiomyopathy complicated with ventricular arrhythmia had an average hospital stay of 9.57 days and 6.85 days;the average number of hospitalizations was 2.13 and 1.40;There were significant differences between 11417.76 yuan and 6432.28 yuan.The cost analysis of the same treatment effect showed that the average hospitalization cost(2354.24 yuan)of the high-dose group treatment was significantly lower than that of the low-dose group(7006.44 yuan)difference.In patients with ineffective results,there was no significant difference in hospitalization costs between the low-dose and high-dose groups.Conclusion The cost of comprehensive treatment for dilated cardiomyopathy complicated with ventricular arrhythmia is higher.After the high-dose bisoprolol combined with fosinopril treatment,the number of hospital days,hospitalizations,and average hospitalization expenses are reduced.Under the same clinical treatment effect,high dose The combination of bisoprolol and fosinopril was more effective than low-dose bisoprolol plus fosinopril.It can be seen that high-dose bisoprolol combined with fosinopril is more feasible in clinical economics and has better application value.

关 键 词：比索洛尔 福辛普利 扩张型心肌病 室性心律失常 费用 

分 类 号：R542.2[医药卫生—心血管疾病] R1-9[医药卫生—内科学]