Quantitative comparisons between relaxation enhanced compressed sensing 3D MERGE and conventional 3D MERGE for vessel wall imaging in equal scan time: preliminary studies  

作　　者：Bo Li Hao Li Li Dong 

机构地区：[1]Center Laboratory,The Third Affiliated Hospital ofNanchang University,Nanchang 330008,China [2]Jiangxi Key Laboratory of Cancer Metastasis and Precision Treatment,The Third Affiliated Hospital of Nanchang University,Nanchang 330008,China [3]Department of Radiology,University of Cambridge,Cambridge CB2 OQQ,UK [4]Department of Radiology,Beijing Anzhen Hospital,Capital Medical University,Beijing 100029,China

出　　处：《Science China(Life Sciences)》2019年第12期1683-1691,共9页中国科学（生命科学英文版）

基　　金：supported by the National Natural Science Foundation of China (81760311);Science and Technology Plan Foundation of the Jiangxi Provincial Health and Family Planning Commission (20184009);Chinese Medicine Research Foundation of the Jiangxi Provincial Health and Family Planning Commission (2017A152)

摘　　要：In this study, we quantitatively compared relaxation enhanced compressed sensing(RECS-3D MERGE) with conventional 3D MERGE techniques on blood suppression efficiency, wall-lumen contrast and plaque burden measurement for carotid atherosclerotic imaging in equal scan time. Twelve patients were recruited in the study. RECS-3D MERGE and conventional 3D MERGE were implemented. 2D DIR-FSE was carried out as a reference standard. The lumen signal-to-tissue ratio(STR) was used as the quantitative measure of blood suppression efficiency. The contrast-to-tissue ratio(CTR) was used as the quantitative measure of wall-lumen contrast. Vessel lumen area(LA) and wall area(WA) were measured for morphological comparisons. The lumen STR of RECS-3D MERGE was significantly lower than that of 3D MERGE while the wall-lumen CTR of RECS-3D MERGE was significantly higher. There were no significant differences in plaque burden measurements between RECS-3D MERGE and 2D DIR-FSE. For comparison between conventional 3D MERGE and 2D DIR-FSE, there were no significant differences in LA measurement. However, the WA of 3D MERGE was significantly larger. The RECS-3D MERGE sequence achieved more sufficient blood suppression and higher image contrast without prolonging the scan time. These improvements lead to more accurate morphological measurements of carotid atherosclerotic imaging.In this study, we quantitatively compared relaxation enhanced compressed sensing(RECS-3 D MERGE) with conventional 3 D MERGE techniques on blood suppression efficiency, wall-lumen contrast and plaque burden measurement for carotid atherosclerotic imaging in equal scan time. Twelve patients were recruited in the study. RECS-3 D MERGE and conventional 3 D MERGE were implemented. 2 D DIR-FSE was carried out as a reference standard. The lumen signal-to-tissue ratio(STR) was used as the quantitative measure of blood suppression efficiency. The contrast-to-tissue ratio(CTR) was used as the quantitative measure of wall-lumen contrast. Vessel lumen area(LA) and wall area(WA) were measured for morphological comparisons. The lumen STR of RECS-3 D MERGE was significantly lower than that of 3 D MERGE while the wall-lumen CTR of RECS-3 D MERGE was significantly higher. There were no significant differences in plaque burden measurements between RECS-3 D MERGE and 2 D DIR-FSE. For comparison between conventional 3 D MERGE and 2 D DIR-FSE, there were no significant differences in LA measurement. However, the WA of 3 D MERGE was significantly larger. The RECS-3 D MERGE sequence achieved more sufficient blood suppression and higher image contrast without prolonging the scan time. These improvements lead to more accurate morphological measurements of carotid atherosclerotic imaging.

关 键 词：RECS-3D MERGE black-blood MR imaging compressed sensing pseudo-centric phase encoding order 

分 类 号：TP3[自动化与计算机技术—计算机科学与技术]