腹腔镜下卵巢巧克力囊肿剥除术中应用垂体后叶素水分离法的效果观察及对卵巢功能的影响  

Effect of pituitrin-water separation in laparoscopic removal of ovarian chocolate cyst and its effect on ovarian function

作　　者：汪玲玲[1] 陈一喆[1] 戴蜜蜜[1] 周伶倒 梅洁[1] 耿筱虹[1] Wang Lingling;Chen Yizhe;Dai Mimi;Zhou Lingli;Mei Jie;Ge Xiaohong(Department of Gynecology,the Second Affiliated Hospital of Wenzhou Medical University,Wenzhou,Zhejiang,325000,China)

机构地区：[1]温州医科大学附属第二医院妇科,325000

出　　处：《中国基层医药》2019年第24期2965-2968,共4页Chinese Journal of Primary Medicine and Pharmacy

基　　金：浙江省温州市科技计划项目(2017Y0885)。

摘　　要：目的 探讨腹腔镜下卵巢巧克力囊肿剥除术中应用垂体后叶素水分离法的效果及对卵巢功能的影响.方法 选择温州医科大学附属第二医院2018年2月至2019年2月收治的择期行腹腔镜下卵巢巧克力囊肿剥除术患者82例为研究对象,采用随机数字表法分为观察组与对照组各41例.对照组行传统腹腔镜下撕拉式剥除卵巢囊肿,观察组采用垂体后叶素水分离法.比较两组围术期指标变化、手术前后血红蛋白(Hb)减少情况、囊肿壁上的正常卵巢组织的阳性率和附着正常卵泡数、术前和术后3个月血清激素水平变化.结果 观察组术中出血量[(58.97 ±8.74)mL]少于对照组[(118.93 ±24.21) mL],手术时间[(57.46 ± 8.27)min]短于对照组[(87.38 ±10.19)min](t=14.916、14.598,均P<0.05);两组术后肛门排气时间差异无统计学意义(P>0.05).观察组手术前后Hb减少[(0.71 ±0.16) g/L]低于对照组[(1.27 ±0.35) g/L] (t=9.318,P<0.05).观察组囊肿壁上的正常卵巢组织的阳性率(21.95%)低于对照组(56.10%),附着正常卵泡数[(2.65 ±0.49)个]少于对照组[(4.86 ±1.24)个](χ^2 =10.045,t=10.613,均P<0.05).观察组术后3个月血清雌二醇(E2 )[(398.21 ±17.84)pmol/L]高于对照组[(367.83 ±15.21)pmol/L],而卵泡刺激素(FSH)[(6.72 ±0.28) mIU/mL]和黄体生成素( LH) [( 5.23 ±0.38) mIU/mL]低于对照组[( 7.19 ± 0.35)mIU/mL、(5.69 ±0.31)mIU/mL](t=8.298、6.714、6.006,均P<0.05).结论 腹腔镜下卵巢巧克力囊肿剥除术中应用垂体后叶素水分离法效果良好,可减轻术中损伤,对Hb影响小,并可改善卵巢储备功能.Objective To investigate the effect of pituitrin-water separation on hemoglobin and ovarian func-tion in laparoscopic ovarian chocolate cyst removal.Methods From February 2018 to February 2019,82 patients with ovarian chocolate cyst removed by laparoscopy were selected from the Second Affiliated Hospital of Wenzhou Medical University.They were randomly divided into observation group and control group according to the digital table,with 41 cases in each group.The control group underwent traditional laparoscopic tear-and-tear ovarian cyst removal,while the observation group underwent pituitrin-water separation.The changes of perioperative indicators ,the decrease of hemoglobin (Hb) before and after operation ,the positive rate of normal ovarian tissue on cyst wall and the number of normal follicles attached to cyst wall ,the changes of serum hormone levels before and after operation were compared between the two groups.Results The amount of bleeding during operation in the observation group [(58.97 ±8.74)mL] was less than that in the control group [(118.93 ±24.21)mL],and the operation time in the observation group[(57.46 ±8.27) min] was shorter than that in the control group [(87.38 ±10.19) min] ,the differences were ststistically significant between the two group ( t =14.916,14.598,all P <0.05 ).There was no statistically significant difference in the time of anal exhaust between the two groups (P>0.05).The decrease of Hb in the observation group [(0.71 ±0.16)g/L] was lower than that in the control group [(1.27 ±0.35) g/L] ( t=9.318,P<0.05).The positive rate of normal ovarian tissue on cyst wall in the observation group (21.95%) was lower than that in the control group (56.10%),the number of normal follicles attached to the cyst wall in the obser-vation group (2.65 ±0.49) was less than that in the control group (4.86 ±1.24) ,the differences were ststistically significant between the two group ( χ^2 =10.045, t =10.613, all P <0.05).The serum level of E2 [( 398.21 ± 17.84)pmol/L] in the observation group w

关 键 词：卵巢囊肿 腹腔镜检查 垂体激素类 后叶 失血 手术 血红蛋白类 卵巢功能试验 雌二醇 卵泡刺激素 黄体激素类 

分 类 号：R71[医药卫生—妇产科学]