外泌体在甲状腺肿瘤中的研究进展  

Review of progress and prospects about exosomes in thyroid tumors research

作　　者：纪飞虹 杜军威[1] 付利军[1] 张丹华 刘森源[1] 焦赞 邱新光[1] Ji Feihong;Du Junwei;Fu Lijun;Zhang Danhua;Liu Senyuan;Jiao Zan;Qiu Xinguang(Department of Thyroid Surgery,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China)

机构地区：[1]郑州大学第一附属医院甲状腺外科,450052

出　　处：《国际外科学杂志》2019年第12期857-861,共5页International Journal of Surgery

基　　金：河南省教育厅项目(18A320008)。

摘　　要：外泌体是在细胞内产生,一种大小介于40~100 nm的微小囊泡,是细胞信号转导的重要载体。甲状腺癌是内分泌系统常见的恶性肿瘤,在甲状腺癌的发生、发展、转移的过程中,外泌体起着调控作用。本文主要就外泌体的相关特点及及外泌体在甲状腺癌的诊治方面的研究进展进行综述。Exosomes are tiny vesicles produced in cells which sizes between 40 to 100 nm.Exosomes are carriers of cell signal transduction.Thyroid cancer is the common malignant tumor in endocrine system.Exosomes show the regulatory role in thyroid cancer about occurrence,development and metastasis.This review focuses on the relevant characteristics of exosomes and the research progress of exosomes in thyroid cancer.

关 键 词：外泌体 甲状腺癌 MIRNA 肿瘤微环境 

分 类 号：R73[医药卫生—肿瘤]