理气活血汤联合西药治疗气滞血瘀型慢性前列腺炎的临床研究  

Clinical study of Liqi Huoxue Decoction combined with Western medicine in the treatment of chronic prostatitis with the symptom of stagnation of qi and blood stasis

作　　者：秦锋 吴升 杨明月[2] QIN Feng;WU Sheng;YANG Mingyue(Department of Urology,Affiliated Hospital of Jiangnan University Wuxi Third People′s Hospital Wuxi Integrated of Traditional Chinese and Western Medicine Hospital,Jiangsu Province,Wuxi 214041,China;Department of Nephrology,Affiliated Hospital of Jiangnan University Wuxi Third People′s Hospital Wuxi Integrated of Traditional Chinese and Western Medicine Hospital,Jiangsu Province,Wuxi 214041,China)

机构地区：[1]江南大学附属医院江苏省无锡市第三人民医院江苏省无锡市中西医结合医院泌尿外科,江苏无锡214041 [2]江南大学附属医院江苏省无锡市第三人民医院江苏省无锡市中西医结合医院肾内科,江苏无锡214041

出　　处：《中国医药导报》2019年第36期123-126,共4页China Medical Herald

基　　金：江苏省卫生计生委科研课题（H201745）;江苏省无锡市卫计委精准医学重点专项（J201810）

摘　　要：目的探讨理气活血汤联合西药治疗气滞血瘀症慢性前列腺炎(CP)的临床效果。方法选取2018年4月~2019年5月无锡市第三人民医院收治的CP患者92例,采用随机数字表法将患者分为研究组(46例)和对照组(46例)。对照组给予常规西药治疗,研究组在对照组基础上联合理气活血汤治疗。比较两组患者临床效果、中医症候积分、炎性因子水平及不良反应发生情况。结果两组患者治疗8周后会阴部疼痛、尿后滴沥、会阴部坠胀、排尿刺痛等症状积分和前列腺液白细胞介素-8(IL-8)、γ-干扰素(IFN-γ)及肿瘤坏死因子-α(TNF-α)水平均显著低于治疗前,且研究组低于对照组,差异有统计学意义(P<0.05)。研究组临床总有效率显著高于对照组,差异有统计学意义(P<0.05)。两组患者不良反应发生率比较,差异无统计学意义(P>0.05)。结论理气活血汤联合西药治疗气滞血瘀型CP患者,效果确切,可迅速改善患者临床症状,减轻机体炎性因子水平,且用药安全性较好。Objective To explore the clinical effect of Liqi Huoxue Decoction combined with Western medicine on chronic prostatitis(CP)with stagnation of qi and blood stasis.Methods A total of 92 CP patients admitted to Wuxi Third People′s Hospital from April 2018 to March 2019 were divided into study group(46 cases)and control group(46 cases)by random number table method.The control group was treated with conventional Western medicine,while the study group was treated with Liqi Huoxue Decoction on the basis of the control group.The curative effect,tradi-tional Chinese medicine symptom score,inflammatory factor levels and the incidence of adverse reactions were com-pared between the two groups.Results After 8 weeks of treatment,the symptom scores of perineum pain,post urine drip,perineum distention,urination tingling and the levels of interleukin-8(IL-8),interferon-γ(IFN-γ)and tumor necrosis factor-α(TNF-α)in prostatic fluid in the two groups were lower than before the treatment,while the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).The total clinical effective rate of the study group was significantly higher than that of the control group,and the difference was statistically significant(P<0.05).There was no difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Liqi Huoxue Decoction combined with Western medicine is effective in the treatment of CP patients with the symptom of stagnation of qi and blood stasis.It can rapidly improve the clinical symptoms of the pa-tients,reduce the levels of inflammatory factors in the body,and the drug is safety.

关 键 词：理气活血汤 西药 气滞血瘀型 慢性前列腺炎 临床效果 

分 类 号：R969.4[医药卫生—药理学]